Matches in Ubergraph for { <http://purl.obolibrary.org/obo/NCIT_C53400> ?p ?o ?g. }
Showing items 1 to 34 of
34
with 100 items per page.
- NCIT_C53400 IAO_0000115 "The sodium salt of bemiparin, a second generation, synthetic, low-molecular-weight heparin (LMWH) with anticoagulant activity. Derived, after depolymerisation and fractionation, from medical-grade porcine unfractionated heparin (UFH), bemiparin has an average molecular weight of 3,600 daltons and has a higher anti-factor Xa/anti-factor IIa ratio (8:1) than first-generation LMWHs. This anticoagulant binds to antithrombin III, thereby enhancing the inactivation of activated factor X (Factor Xa) and, to a lesser extent, activated factor II (Factor IIa). Compared to unfractionated heparins, the use of bemiparin is associated with lower incidences of major bleeding, osteoporosis, and heparin-induced thrombocytopenia. Bemiparin also promotes a greater release of tissue factor pathway inhibitor than UFH or dalteparin." @default.
- NCIT_C53400 NCIT_A6 NCIT_C173512 @default.
- NCIT_C53400 NCIT_NHC0 "C53400" @default.
- NCIT_C53400 NCIT_P106 "Organic Chemical" @default.
- NCIT_C53400 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C53400 NCIT_P108 "Bemiparin Sodium" @default.
- NCIT_C53400 NCIT_P207 "C1529923" @default.
- NCIT_C53400 NCIT_P319 "P59JKU02CE" @default.
- NCIT_C53400 NCIT_P322 "FDA" @default.
- NCIT_C53400 NCIT_P329 "463367" @default.
- NCIT_C53400 NCIT_P330 "463367" @default.
- NCIT_C53400 NCIT_P366 "Bemiparin_Sodium" @default.
- NCIT_C53400 NCIT_P399 "463367" @default.
- NCIT_C53400 normalizedInformationContent "100" @default.
- NCIT_C53400 referenceCount "1" @default.
- NCIT_C53400 hasExactSynonym "BEMIPARIN SODIUM" @default.
- NCIT_C53400 hasExactSynonym "Badyket" @default.
- NCIT_C53400 hasExactSynonym "Bemiparin Sodium" @default.
- NCIT_C53400 hasExactSynonym "Hibor" @default.
- NCIT_C53400 hasExactSynonym "Ivor" @default.
- NCIT_C53400 hasExactSynonym "Zibor" @default.
- NCIT_C53400 inSubset NCIT_C173381 @default.
- NCIT_C53400 inSubset NCIT_C173383 @default.
- NCIT_C53400 inSubset NCIT_C176424 @default.
- NCIT_C53400 inSubset NCIT_C63923 @default.
- NCIT_C53400 type Class @default.
- NCIT_C53400 isDefinedBy ncit.owl @default.
- NCIT_C53400 label "Bemiparin Sodium" @default.
- NCIT_C53400 subClassOf NCIT_C1908 @default.
- NCIT_C53400 subClassOf NCIT_C1909 @default.
- NCIT_C53400 subClassOf NCIT_C2578 @default.
- NCIT_C53400 subClassOf NCIT_C263 @default.
- NCIT_C53400 subClassOf NCIT_C53400 @default.
- NCIT_C53400 subClassOf NCIT_C78275 @default.