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- NCIT_C53408 IAO_0000115 "The hydrochloride salt of alfuzosin, a quinazoline compound with smooth muscle-relaxing activity. Alfuzosin selectively binds to and antagonizes post-synaptic alpha-1-adrenoreceptors in smooth muscle of the prostate, bladder base, bladder neck, prostatic capsule, and prostatic urethra, initiating relaxation of smooth muscle and resulting in improvement of urine flow and the symptoms of benign prostatic hyperplasia (BPH). This agent also blocks alpha-1-adrenoreceptors in peripheral vascular smooth muscle, resulting in vasodilatation and a decrease in peripheral vascular resistance." @default.
- NCIT_C53408 NCIT_A6 NCIT_C61627 @default.
- NCIT_C53408 NCIT_NHC0 "C53408" @default.
- NCIT_C53408 NCIT_P106 "Organic Chemical" @default.
- NCIT_C53408 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C53408 NCIT_P108 "Alfuzosin Hydrochloride" @default.
- NCIT_C53408 NCIT_P207 "C0102130" @default.
- NCIT_C53408 NCIT_P210 "81403-68-1" @default.
- NCIT_C53408 NCIT_P319 "75046A1XTN" @default.
- NCIT_C53408 NCIT_P322 "FDA" @default.
- NCIT_C53408 NCIT_P329 "465648" @default.
- NCIT_C53408 NCIT_P330 "465648" @default.
- NCIT_C53408 NCIT_P350 "C19H27N5O4.ClH" @default.
- NCIT_C53408 NCIT_P366 "Alfuzosin_Hydrochloride" @default.
- NCIT_C53408 NCIT_P368 "CHEBI:32286" @default.
- NCIT_C53408 NCIT_P399 "465648" @default.
- NCIT_C53408 normalizedInformationContent "100" @default.
- NCIT_C53408 referenceCount "1" @default.
- NCIT_C53408 hasExactSynonym "(+/-)-N-(3-((4-amino-6,7-dimethoxyquinazolin-2-yl)(methyl)amino)propyl)tetrahydrofuran-2-carboxamide Monohydrochloride" @default.
- NCIT_C53408 hasExactSynonym "(R,S)-N-[3-[(4-Amino-6,7-dimethoxy-2-quinazolinyl)methylamino] propyl]tetrahydro-2-furancarboxamide Hydrochloride" @default.
- NCIT_C53408 hasExactSynonym "ALFUZOSIN HYDROCHLORIDE" @default.
- NCIT_C53408 hasExactSynonym "Alfuzosin Hydrochloride" @default.
- NCIT_C53408 hasExactSynonym "SL 77499-10" @default.
- NCIT_C53408 hasExactSynonym "Uroxatral" @default.
- NCIT_C53408 inSubset NCIT_C176424 @default.
- NCIT_C53408 inSubset NCIT_C63923 @default.
- NCIT_C53408 type Class @default.
- NCIT_C53408 isDefinedBy ncit.owl @default.
- NCIT_C53408 label "Alfuzosin Hydrochloride" @default.
- NCIT_C53408 subClassOf NCIT_C1908 @default.
- NCIT_C53408 subClassOf NCIT_C1909 @default.
- NCIT_C53408 subClassOf NCIT_C29713 @default.
- NCIT_C53408 subClassOf NCIT_C29747 @default.
- NCIT_C53408 subClassOf NCIT_C53408 @default.
- NCIT_C53408 subClassOf NCIT_C72900 @default.
- NCIT_C53408 subClassOf NCIT_C78272 @default.