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- NCIT_C53434 IAO_0000115 "A phytonutrient and plant indole found in cruciferous vegetables including broccoli, Brussels sprouts, cabbage, cauliflower and kale, with potential anti-androgenic and antineoplastic activities. As a dimer of indole-3-carbinol, diindolylmethane (DIM) promotes beneficial estrogen metabolism in both sexes by reducing the levels of 16-hydroxy estrogen metabolites and increasing the formation of 2-hydroxy estrogen metabolites, resulting in increased antioxidant activity. Although this agent induces apoptosis in tumor cells in vitro, the exact mechanism by which DIM exhibits its antineoplastic activity in vivo is unknown." @default.
- NCIT_C53434 NCIT_A32 NCIT_C1909 @default.
- NCIT_C53434 NCIT_NHC0 "C53434" @default.
- NCIT_C53434 NCIT_P106 "Organic Chemical" @default.
- NCIT_C53434 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C53434 NCIT_P107 "Diindolylmethane" @default.
- NCIT_C53434 NCIT_P108 "Diindolylmethane" @default.
- NCIT_C53434 NCIT_P207 "C1100708" @default.
- NCIT_C53434 NCIT_P210 "1968-05-4" @default.
- NCIT_C53434 NCIT_P319 "SSZ9HQT61Z" @default.
- NCIT_C53434 NCIT_P322 "CTRP" @default.
- NCIT_C53434 NCIT_P322 "FDA" @default.
- NCIT_C53434 NCIT_P322 "GDC" @default.
- NCIT_C53434 NCIT_P325 "A substance being studied in the treatment of prostate cancer and in the prevention of cervical cancer. Diindolylmethane is found in cruciferous vegetables like broccoli, brussels sprouts, cauliflower, cabbage, and kale. It is a type of plant indole." @default.
- NCIT_C53434 NCIT_P329 "462587" @default.
- NCIT_C53434 NCIT_P330 "462587" @default.
- NCIT_C53434 NCIT_P366 "Diindolylmethane" @default.
- NCIT_C53434 NCIT_P368 "CHEBI:50182" @default.
- NCIT_C53434 NCIT_P375 "Diindolylmethane" @default.
- NCIT_C53434 NCIT_P399 "462587" @default.
- NCIT_C53434 normalizedInformationContent "100" @default.
- NCIT_C53434 referenceCount "1" @default.
- NCIT_C53434 hasExactSynonym "3,3'-DIINDOLYLMETHANE" @default.
- NCIT_C53434 hasExactSynonym "3,3'-Diindolymethane" @default.
- NCIT_C53434 hasExactSynonym "3,3'-Methylenebis-1H-indole" @default.
- NCIT_C53434 hasExactSynonym "CCRIS 5806" @default.
- NCIT_C53434 hasExactSynonym "DIM" @default.
- NCIT_C53434 hasExactSynonym "DIM-Plus" @default.
- NCIT_C53434 hasExactSynonym "DIMPRO" @default.
- NCIT_C53434 hasExactSynonym "Di-Indoly Methane" @default.
- NCIT_C53434 hasExactSynonym "Diindolylmethane" @default.
- NCIT_C53434 hasExactSynonym "diindolylmethane" @default.
- NCIT_C53434 inSubset NCIT_C116977 @default.
- NCIT_C53434 inSubset NCIT_C116978 @default.
- NCIT_C53434 inSubset NCIT_C128784 @default.
- NCIT_C53434 inSubset NCIT_C157711 @default.
- NCIT_C53434 inSubset NCIT_C157712 @default.
- NCIT_C53434 inSubset NCIT_C176424 @default.
- NCIT_C53434 inSubset NCIT_C177537 @default.
- NCIT_C53434 inSubset NCIT_C63923 @default.
- NCIT_C53434 type Class @default.
- NCIT_C53434 isDefinedBy ncit.owl @default.
- NCIT_C53434 label "Diindolylmethane" @default.
- NCIT_C53434 subClassOf NCIT_C1892 @default.
- NCIT_C53434 subClassOf NCIT_C1908 @default.
- NCIT_C53434 subClassOf NCIT_C1909 @default.
- NCIT_C53434 subClassOf NCIT_C1913 @default.
- NCIT_C53434 subClassOf NCIT_C1915 @default.
- NCIT_C53434 subClassOf NCIT_C1933 @default.
- NCIT_C53434 subClassOf NCIT_C53434 @default.
- NCIT_C53434 subClassOf NCIT_C54630 @default.
- NCIT_C53434 subClassOf NCIT_C54677 @default.
- NCIT_C53434 subClassOf NCIT_C718 @default.