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- NCIT_C5420 IAO_0000115 "A sensory neuropathy caused by the effects of a distant neoplasm (usually a small cell carcinoma). It is usually caused by the production of anti-neuronal autoantibodies: anti-Hu (ANNA-1) or anti-CV2 (CRMP-5), which result in cytotoxic T-cell mediated destruction of dorsal root ganglia. It is the most common clinical presentation of paraneoplastic encephalomyelitis. Clinical signs include asymmetric paresthesia of the face, trunk and proximal extremities followed by lancinating pain, vibrioceptive and proprioceptive impairment, and muted reflexes. Clinical course usually follows a progressive neurologic deterioration which stabilizes at a level of severe, permanent disability." @default.
- NCIT_C5420 NCIT_NHC0 "C5420" @default.
- NCIT_C5420 NCIT_P106 "Disease or Syndrome" @default.
- NCIT_C5420 NCIT_P108 "Paraneoplastic Subacute Sensory Neuronopathy" @default.
- NCIT_C5420 NCIT_P207 "C1335344" @default.
- NCIT_C5420 NCIT_P366 "Paraneoplastic_Subacute_Sensory_Neuronopathy" @default.
- NCIT_C5420 NCIT_R100 NCIT_C12219 @default.
- NCIT_C5420 NCIT_R100 NCIT_C12755 @default.
- NCIT_C5420 NCIT_R100 NCIT_C12919 @default.
- NCIT_C5420 normalizedInformationContent "100" @default.
- NCIT_C5420 referenceCount "1" @default.
- NCIT_C5420 hasExactSynonym "Paraneoplastic Subacute Sensory Neuronopathy" @default.
- NCIT_C5420 hasExactSynonym "Paraneoplastic Subacute Sensory Neuropathy" @default.
- NCIT_C5420 type Class @default.
- NCIT_C5420 isDefinedBy ncit.owl @default.
- NCIT_C5420 label "Paraneoplastic Subacute Sensory Neuronopathy" @default.
- NCIT_C5420 subClassOf NCIT_C26835 @default.
- NCIT_C5420 subClassOf NCIT_C26951 @default.
- NCIT_C5420 subClassOf NCIT_C27551 @default.
- NCIT_C5420 subClassOf NCIT_C28193 @default.
- NCIT_C5420 subClassOf NCIT_C2991 @default.
- NCIT_C5420 subClassOf NCIT_C3311 @default.
- NCIT_C5420 subClassOf NCIT_C3981 @default.
- NCIT_C5420 subClassOf NCIT_C4731 @default.
- NCIT_C5420 subClassOf NCIT_C5420 @default.
- NCIT_C5420 subClassOf NCIT_C7057 @default.
- NCIT_C5420 subClassOf NCIT_C8278 @default.