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- NCIT_C544 IAO_0000115 "A synthetic cytotoxic s-triazine derivative similar in structure to alkylating agent triethylenemelamin with antineoplastic activity. Although the precise mechanism by which altretamine exerts its cytotoxic effect is unknown, N-demethylation of altretamine may produce reactive intermediates which covalently bind to DNA, resulting in DNA damage. (NCI04)" @default.
- NCIT_C544 NCIT_A32 NCIT_C1909 @default.
- NCIT_C544 NCIT_NHC0 "C544" @default.
- NCIT_C544 NCIT_P106 "Organic Chemical" @default.
- NCIT_C544 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C544 NCIT_P108 "Altretamine" @default.
- NCIT_C544 NCIT_P175 "13875" @default.
- NCIT_C544 NCIT_P207 "C0019453" @default.
- NCIT_C544 NCIT_P210 "645-05-6" @default.
- NCIT_C544 NCIT_P319 "Q8BIH59O7H" @default.
- NCIT_C544 NCIT_P322 "FDA" @default.
- NCIT_C544 NCIT_P322 "GDC" @default.
- NCIT_C544 NCIT_P325 "An anticancer drug that belongs to the family of drugs called alkylating agents." @default.
- NCIT_C544 NCIT_P329 "39475" @default.
- NCIT_C544 NCIT_P330 "39475" @default.
- NCIT_C544 NCIT_P350 "C9H18N6" @default.
- NCIT_C544 NCIT_P366 "Altretamine" @default.
- NCIT_C544 NCIT_P368 "CHEBI:24564" @default.
- NCIT_C544 NCIT_P375 "Altretamine" @default.
- NCIT_C544 NCIT_P399 "39475" @default.
- NCIT_C544 normalizedInformationContent "77.493725483418473" @default.
- NCIT_C544 referenceCount "30" @default.
- NCIT_C544 hasExactSynonym "2,4,6-Tris(dimethylamino)-s-triazine" @default.
- NCIT_C544 hasExactSynonym "2,4,6-tris(dimethylamino)-s-triazine" @default.
- NCIT_C544 hasExactSynonym "ALTRETAMINE" @default.
- NCIT_C544 hasExactSynonym "Altretamine" @default.
- NCIT_C544 hasExactSynonym "ENT 50852" @default.
- NCIT_C544 hasExactSynonym "ENT-50852" @default.
- NCIT_C544 hasExactSynonym "HMM" @default.
- NCIT_C544 hasExactSynonym "HXM" @default.
- NCIT_C544 hasExactSynonym "Hemel" @default.
- NCIT_C544 hasExactSynonym "Hexalen" @default.
- NCIT_C544 hasExactSynonym "Hexaloids" @default.
- NCIT_C544 hasExactSynonym "Hexamethylamine" @default.
- NCIT_C544 hasExactSynonym "Hexamethylmelamine" @default.
- NCIT_C544 hasExactSynonym "Hexastat" @default.
- NCIT_C544 hasExactSynonym "Hexinawas" @default.
- NCIT_C544 hasExactSynonym "N,N,N',N',N",N"-hexamethyl-1,3,5-triazine-2,4,6-triamine" @default.
- NCIT_C544 hasExactSynonym "N,n,n',N"N"-hexamethyl-1,3,5,-triazine-2,4,6,-triamine" @default.
- NCIT_C544 hasExactSynonym "RB-1515" @default.
- NCIT_C544 hasExactSynonym "WR-95704" @default.
- NCIT_C544 hasExactSynonym "altretamine" @default.
- NCIT_C544 hasExactSynonym "s-Triazine, 2,4,6-tris(dimethylamino)-" @default.
- NCIT_C544 inSubset NCIT_C128784 @default.
- NCIT_C544 inSubset NCIT_C157711 @default.
- NCIT_C544 inSubset NCIT_C157712 @default.
- NCIT_C544 inSubset NCIT_C176424 @default.
- NCIT_C544 inSubset NCIT_C177537 @default.
- NCIT_C544 inSubset NCIT_C63923 @default.
- NCIT_C544 type Class @default.
- NCIT_C544 isDefinedBy ncit.owl @default.
- NCIT_C544 label "Altretamine" @default.
- NCIT_C544 subClassOf NCIT_C1590 @default.
- NCIT_C544 subClassOf NCIT_C186664 @default.
- NCIT_C544 subClassOf NCIT_C1908 @default.
- NCIT_C544 subClassOf NCIT_C1909 @default.
- NCIT_C544 subClassOf NCIT_C274 @default.
- NCIT_C544 subClassOf NCIT_C2842 @default.
- NCIT_C544 subClassOf NCIT_C292 @default.
- NCIT_C544 subClassOf NCIT_C544 @default.