Matches in Ubergraph for { <http://purl.obolibrary.org/obo/NCIT_C54432> ?p ?o ?g. }
- NCIT_C54432 IAO_0000115 "Human DLEC1 wild-type allele is located within 3p22-p21.3 and is approximately 261 kb in length. This allele, which encodes deleted in lung and esophageal cancer 1 protein, plays a role in tumor suppression. This allele is frequently deleted or abberantly expressed in several cancers." @default.
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- NCIT_C54432 NCIT_P100 "604050" @default.
- NCIT_C54432 NCIT_P102 "NM_005106" @default.
- NCIT_C54432 NCIT_P106 "Gene or Genome" @default.
- NCIT_C54432 NCIT_P108 "DLEC1 wt Allele" @default.
- NCIT_C54432 NCIT_P207 "C1705128" @default.
- NCIT_C54432 NCIT_P211 "negative regulation of cell proliferation" @default.
- NCIT_C54432 NCIT_P321 "9940" @default.
- NCIT_C54432 NCIT_P366 "DLEC1_wt_Allele" @default.
- NCIT_C54432 NCIT_P96 "DLEC1 Protein" @default.
- NCIT_C54432 NCIT_P98 "DLEC1 Gene contains 37 exons that encode numerous alternatively spliced, widely expressed 6-8-kb mRNAs (DLEC1-N, -L, -S). DLEC1-N1 and -N2 contain all 37 exons and encode a full-length 1755-amino acid 195.8-kD DLEC1 Protein, a likely negative regulator of cell proliferation. DLEC1-S1, -S2, and -S3 lack exons 11, 13, or 36 and encode frame-shifted protein. DLEC1-L1 and -L2 include all or part of intron 13 and encode prematurely truncated proteins. DLC1 expression appears to suppress growth of some cancer cell lines. Aberrant transcription may be involved in carcinogenesis of the lung, esophagus, and kidney." @default.
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- NCIT_C54432 hasExactSynonym "CFAP81" @default.
- NCIT_C54432 hasExactSynonym "DLC-1" @default.
- NCIT_C54432 hasExactSynonym "DLC1" @default.
- NCIT_C54432 hasExactSynonym "DLEC1 wt Allele" @default.
- NCIT_C54432 hasExactSynonym "DLEC1" @default.
- NCIT_C54432 hasExactSynonym "Deleted in Lung and Esophageal Cancer 1 wt Allele" @default.
- NCIT_C54432 hasExactSynonym "F56" @default.