Matches in Ubergraph for { <http://purl.obolibrary.org/obo/NCIT_C560> ?p ?o ?g. }
- NCIT_C560 IAO_0000115 "A monohydroxyl-substituted urea (hydroxycarbamate) antimetabolite. Hydroxyurea selectively inhibits ribonucleoside diphosphate reductase, an enzyme required to convert ribonucleoside diphosphates into deoxyribonucleoside diphosphates, thereby preventing cells from leaving the G1/S phase of the cell cycle. This agent also exhibits radiosensitizing activity by maintaining cells in the radiation-sensitive G1 phase and interfering with DNA repair. (NCI04)" @default.
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- NCIT_C560 NCIT_P302 "Chronic Myelogenous Leukemia; Head and Neck Cancer; Malignant Melanoma; Ovarian Carcinoma; Sickle Cell Anemia; Adjuvant in Retroviral Therapy." @default.
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- NCIT_C560 normalizedInformationContent "74.665259135057511" @default.
- NCIT_C560 referenceCount "46" @default.
- NCIT_C560 hasExactSynonym "Droxia" @default.
- NCIT_C560 hasExactSynonym "HYDROXYUREA" @default.
- NCIT_C560 hasExactSynonym "Hydrea" @default.
- NCIT_C560 hasExactSynonym "Hydroxycarbamide" @default.
- NCIT_C560 hasExactSynonym "Hydroxyurea" @default.
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- NCIT_C560 hasExactSynonym "Onco-Carbide" @default.
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- NCIT_C560 label "Hydroxyurea" @default.
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