Matches in Ubergraph for { <http://purl.obolibrary.org/obo/NCIT_C60806> ?p ?o ?g. }
Showing items 1 to 22 of
22
with 100 items per page.
- NCIT_C60806 IAO_0000115 "A synthetic oligodeoxynucleotide containing multiple repeats of unmethylated CpG motifs (CpG ODN) with immunostimulatory activity. Upon entering the cell via endocytosis, CpG-28 activates numerous signaling transduction pathways resulting in the release of multiple cytokines. CpG-28 has immunomodulatory properties with direct activation of B-lymphocytes, dendritic and NK cells resulting in the stimulation of innate immunity and antibody-dependant cell cytotoxicity (ADCC). Additionally, this agent indirectly modulates T-cell responses though the release of cytokines (IL-12 and IFN gamma) to induce a preferential shift to the Th1 (helper) phenotype resulting in enhanced CD8+ cellular cytotoxicity." @default.
- NCIT_C60806 NCIT_NHC0 "C60806" @default.
- NCIT_C60806 NCIT_P106 "Nucleic Acid, Nucleoside, or Nucleotide" @default.
- NCIT_C60806 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C60806 NCIT_P108 "CpG-28 Oligodeoxynucleotide" @default.
- NCIT_C60806 NCIT_P200 "Immunostimulant" @default.
- NCIT_C60806 NCIT_P200 "Phosphorothioate_Oligonucleotide" @default.
- NCIT_C60806 NCIT_P203 "Chemicals_and_Drugs_Kind" @default.
- NCIT_C60806 NCIT_P310 "Retired_Concept" @default.
- NCIT_C60806 NCIT_P98 "See 'CpG oligodeoxynucleotide'" @default.
- NCIT_C60806 normalizedInformationContent "100" @default.
- NCIT_C60806 referenceCount "1" @default.
- NCIT_C60806 hasExactSynonym "CpG ODN" @default.
- NCIT_C60806 hasExactSynonym "CpG-28 Oligodeoxynucleotide" @default.
- NCIT_C60806 hasExactSynonym "CpG-28" @default.
- NCIT_C60806 type Class @default.
- NCIT_C60806 isDefinedBy ncit.owl @default.
- NCIT_C60806 label "CpG-28 Oligodeoxynucleotide" @default.
- NCIT_C60806 subClassOf NCIT_C28428 @default.
- NCIT_C60806 subClassOf NCIT_C60806 @default.
- NCIT_C60806 subClassOf NCIT_C83483 @default.
- NCIT_C60806 deprecated "true" @default.