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- NCIT_C60810 IAO_0000115 "The sodium salt of a low molecular weight heparin (LMWH), obtained by controlled enzymatic depolymerization of heparin from porcine intestinal mucosa, with antithrombotic properties. Tinzaparin is a potent inhibitor of several activated coagulation factors, especially Factors Xa and IIa (thrombin); its primary activity is mediated through the plasma protease inhibitor antithrombin. In addition, this agent may inhibit angiogenesis through: 1) competitive binding of the heparin-binding sites on endothelial cells for the proangiogenic cytokines vascular endothelial growth factor (VEGF) and beta-fibroblast growth factor (beta-FGF) and 2) increasing the release of tissue factor pathway inhibitor (TFPI), a negative regulator of angiogenesis." @default.
- NCIT_C60810 NCIT_A32 NCIT_C1909 @default.
- NCIT_C60810 NCIT_A6 NCIT_C87297 @default.
- NCIT_C60810 NCIT_NHC0 "C60810" @default.
- NCIT_C60810 NCIT_P106 "Organic Chemical" @default.
- NCIT_C60810 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C60810 NCIT_P107 "Tinzaparin Sodium" @default.
- NCIT_C60810 NCIT_P108 "Tinzaparin Sodium" @default.
- NCIT_C60810 NCIT_P207 "C0354599" @default.
- NCIT_C60810 NCIT_P210 "9041-08-1" @default.
- NCIT_C60810 NCIT_P302 "Treatment of acute symptomatic deep venous thrombosis (DVT) with or without a pulmonary embolism (PE), in conjunction with warfarin." @default.
- NCIT_C60810 NCIT_P319 "3S182ET3UA" @default.
- NCIT_C60810 NCIT_P322 "CTRP" @default.
- NCIT_C60810 NCIT_P322 "FDA" @default.
- NCIT_C60810 NCIT_P322 "GDC" @default.
- NCIT_C60810 NCIT_P325 "A drug that is used with another drug, warfarin, to treat blood clots that form deep in the veins and to prevent new blood clots from forming. It is a type of anticoagulant." @default.
- NCIT_C60810 NCIT_P329 "467737" @default.
- NCIT_C60810 NCIT_P330 "467737" @default.
- NCIT_C60810 NCIT_P350 "(C14H18NO11)n.2(C12H15NO13S)n.3Na.3O3S" @default.
- NCIT_C60810 NCIT_P366 "Tinzaparin" @default.
- NCIT_C60810 NCIT_P375 "Tinzaparin Sodium" @default.
- NCIT_C60810 NCIT_P399 "467737" @default.
- NCIT_C60810 normalizedInformationContent "100" @default.
- NCIT_C60810 referenceCount "1" @default.
- NCIT_C60810 hasExactSynonym "Enzyme Depolymerized Heparin (MW 6500)" @default.
- NCIT_C60810 hasExactSynonym "Inno-hep" @default.
- NCIT_C60810 hasExactSynonym "Innohep" @default.
- NCIT_C60810 hasExactSynonym "LNH-1" @default.
- NCIT_C60810 hasExactSynonym "Logiparin" @default.
- NCIT_C60810 hasExactSynonym "TINZAPARIN SODIUM" @default.
- NCIT_C60810 hasExactSynonym "Tinzaparin Sodium Injection" @default.
- NCIT_C60810 hasExactSynonym "Tinzaparin Sodium" @default.
- NCIT_C60810 hasExactSynonym "Tinzaparin" @default.
- NCIT_C60810 hasExactSynonym "tinzaparin sodium" @default.
- NCIT_C60810 inSubset NCIT_C116977 @default.
- NCIT_C60810 inSubset NCIT_C116978 @default.
- NCIT_C60810 inSubset NCIT_C128784 @default.
- NCIT_C60810 inSubset NCIT_C157711 @default.
- NCIT_C60810 inSubset NCIT_C157712 @default.
- NCIT_C60810 inSubset NCIT_C173381 @default.
- NCIT_C60810 inSubset NCIT_C173383 @default.
- NCIT_C60810 inSubset NCIT_C176424 @default.
- NCIT_C60810 inSubset NCIT_C177537 @default.
- NCIT_C60810 inSubset NCIT_C63923 @default.
- NCIT_C60810 type Class @default.
- NCIT_C60810 isDefinedBy ncit.owl @default.
- NCIT_C60810 label "Tinzaparin Sodium" @default.
- NCIT_C60810 subClassOf NCIT_C1742 @default.
- NCIT_C60810 subClassOf NCIT_C1908 @default.
- NCIT_C60810 subClassOf NCIT_C1909 @default.
- NCIT_C60810 subClassOf NCIT_C2578 @default.
- NCIT_C60810 subClassOf NCIT_C263 @default.
- NCIT_C60810 subClassOf NCIT_C274 @default.
- NCIT_C60810 subClassOf NCIT_C60810 @default.
- NCIT_C60810 subClassOf NCIT_C78275 @default.