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- NCIT_C60878 IAO_0000115 "Human HMGCR wild-type allele is located within 5q13.3-q14 and is approximately 25 kb in length. This allele, which encodes 3-hydroxy-3-methylglutaryl-coenzyme A reductase protein, plays a role in the regulation of cholesterol biosynthesis." @default.
- NCIT_C60878 NCIT_NHC0 "C60878" @default.
- NCIT_C60878 NCIT_P100 "142910" @default.
- NCIT_C60878 NCIT_P102 "NM_000859" @default.
- NCIT_C60878 NCIT_P106 "Gene or Genome" @default.
- NCIT_C60878 NCIT_P107 "HMGCR wt Allele" @default.
- NCIT_C60878 NCIT_P108 "HMGCR wt Allele" @default.
- NCIT_C60878 NCIT_P207 "C1881028" @default.
- NCIT_C60878 NCIT_P321 "3156" @default.
- NCIT_C60878 NCIT_P322 "CTRP" @default.
- NCIT_C60878 NCIT_P366 "HMGCR_wt_Allele" @default.
- NCIT_C60878 NCIT_P98 "Statins, a class of hypolipidemic agents, are inhibitors of 3-hydroxy-3-methylglutaryl-coenzyme A reductase protein. These drugs are used to lower cholesterol levels in individuals who exhibit hypercholesterolemia and, therefore, are at risk for cardiovascular disease. Heritable polymorphisms in the HMGCR gene are associated with the reduced efficacy of statin therapy in lowering cholesterol levels." @default.
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- NCIT_C60878 NCIT_R41 NCIT_C14182 @default.
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- NCIT_C60878 normalizedInformationContent "100" @default.
- NCIT_C60878 referenceCount "1" @default.
- NCIT_C60878 hasExactSynonym "3-Hydroxy-3-Methylglutaryl CoA Reductase (NADPH) Gene" @default.
- NCIT_C60878 hasExactSynonym "3-Hydroxy-3-Methylglutaryl-Coenzyme A Reductase wt Allele" @default.
- NCIT_C60878 hasExactSynonym "HMGCR wt Allele" @default.
- NCIT_C60878 hasExactSynonym "Hydroxymethylglutaryl-CoA Reductase Gene" @default.
- NCIT_C60878 hasExactSynonym "LDLCQ3" @default.
- NCIT_C60878 inSubset NCIT_C116977 @default.
- NCIT_C60878 inSubset NCIT_C142799 @default.
- NCIT_C60878 inSubset NCIT_C142800 @default.
- NCIT_C60878 type Class @default.
- NCIT_C60878 isDefinedBy ncit.owl @default.
- NCIT_C60878 label "HMGCR wt Allele" @default.
- NCIT_C60878 subClassOf NCIT_C16612 @default.
- NCIT_C60878 subClassOf NCIT_C21281 @default.
- NCIT_C60878 subClassOf NCIT_C25939 @default.
- NCIT_C60878 subClassOf NCIT_C60877 @default.
- NCIT_C60878 subClassOf NCIT_C60878 @default.
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- NCIT_C60878 equivalentClass Bbee93227e5f437e539643704d0e175e6 @default.