Matches in Ubergraph for { <http://purl.obolibrary.org/obo/NCIT_C61075> ?p ?o ?g. }
Showing items 1 to 51 of
51
with 100 items per page.
- NCIT_C61075 IAO_0000115 "An orally bioavailable, highly selective small molecule inhibitor of the serine/threonine protein kinase Aurora A kinase with potential antineoplastic activity. Auora kinase inhibitor MLN8054 binds to and inhibits Aurora kinase A, resulting in disruption of the assembly of the mitotic spindle apparatus, disruption of chromosome segregation, and inhibition of cell proliferation. Aurora A localizes in mitosis to the spindle poles and to spindle microtubules and is thought to regulate spindle assembly. Aberrant expression of Aurora kinases occurs in a wide variety of cancers, including colon and breast cancers." @default.
- NCIT_C61075 NCIT_A32 NCIT_C1909 @default.
- NCIT_C61075 NCIT_NHC0 "C61075" @default.
- NCIT_C61075 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C61075 NCIT_P108 "Aurora Kinase Inhibitor MLN8054" @default.
- NCIT_C61075 NCIT_P207 "C1831780" @default.
- NCIT_C61075 NCIT_P210 "869363-13-3" @default.
- NCIT_C61075 NCIT_P319 "BX854EHD63" @default.
- NCIT_C61075 NCIT_P322 "FDA" @default.
- NCIT_C61075 NCIT_P322 "GDC" @default.
- NCIT_C61075 NCIT_P329 "473901" @default.
- NCIT_C61075 NCIT_P330 "473901" @default.
- NCIT_C61075 NCIT_P366 "MLN8054" @default.
- NCIT_C61075 NCIT_P375 "Aurora Kinase Inhibitor MLN8054" @default.
- NCIT_C61075 NCIT_P399 "473901" @default.
- NCIT_C61075 NCIT_R146 NCIT_C16554 @default.
- NCIT_C61075 NCIT_R146 NCIT_C16984 @default.
- NCIT_C61075 NCIT_R146 NCIT_C17018 @default.
- NCIT_C61075 NCIT_R146 NCIT_C17021 @default.
- NCIT_C61075 NCIT_R146 NCIT_C17210 @default.
- NCIT_C61075 NCIT_R146 NCIT_C17325 @default.
- NCIT_C61075 NCIT_R146 NCIT_C20027 @default.
- NCIT_C61075 NCIT_R146 NCIT_C26548 @default.
- NCIT_C61075 NCIT_R146 NCIT_C30006 @default.
- NCIT_C61075 normalizedInformationContent "100" @default.
- NCIT_C61075 referenceCount "1" @default.
- NCIT_C61075 hasExactSynonym "Aurora Kinase Inhibitor MLN8054" @default.
- NCIT_C61075 hasExactSynonym "Benzoic Acid, 4-((9-Chloro-7-(2,6-difluorophenyl)-5H-pyrimido(5,4-d)(2)benzazepin-2-yl)amino)-" @default.
- NCIT_C61075 hasExactSynonym "MLN 8054" @default.
- NCIT_C61075 hasExactSynonym "MLN-8054" @default.
- NCIT_C61075 hasExactSynonym "MLN8054" @default.
- NCIT_C61075 inSubset NCIT_C128784 @default.
- NCIT_C61075 inSubset NCIT_C157711 @default.
- NCIT_C61075 inSubset NCIT_C157712 @default.
- NCIT_C61075 inSubset NCIT_C176424 @default.
- NCIT_C61075 inSubset NCIT_C177537 @default.
- NCIT_C61075 inSubset NCIT_C63923 @default.
- NCIT_C61075 type Class @default.
- NCIT_C61075 isDefinedBy ncit.owl @default.
- NCIT_C61075 label "Aurora Kinase Inhibitor MLN8054" @default.
- NCIT_C61075 subClassOf NCIT_C129824 @default.
- NCIT_C61075 subClassOf NCIT_C129825 @default.
- NCIT_C61075 subClassOf NCIT_C1404 @default.
- NCIT_C61075 subClassOf NCIT_C1908 @default.
- NCIT_C61075 subClassOf NCIT_C1909 @default.
- NCIT_C61075 subClassOf NCIT_C2189 @default.
- NCIT_C61075 subClassOf NCIT_C274 @default.
- NCIT_C61075 subClassOf NCIT_C471 @default.
- NCIT_C61075 subClassOf NCIT_C61074 @default.
- NCIT_C61075 subClassOf NCIT_C61075 @default.
- NCIT_C61075 subClassOf NCIT_C62556 @default.