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- NCIT_C61319 IAO_0000115 "The lactate salt of tozasertib, a synthetic, small-molecule Aurora kinase inhibitor with potential antitumor activity. Tozasertib binds to and inhibits Aurora kinases (AKs), thereby inducing apoptosis in tumor cells in which AKs are overexpressed. AKs, a family of serine-threonine kinases, are essential for mitotic progression, spindle formation, centrosome maturation, chromosomal segregation, and cytokinesis." @default.
- NCIT_C61319 NCIT_A32 NCIT_C1909 @default.
- NCIT_C61319 NCIT_A6 NCIT_C98053 @default.
- NCIT_C61319 NCIT_A7 NCIT_C30006 @default.
- NCIT_C61319 NCIT_A7 NCIT_C68596 @default.
- NCIT_C61319 NCIT_A7 NCIT_C95267 @default.
- NCIT_C61319 NCIT_NHC0 "C61319" @default.
- NCIT_C61319 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C61319 NCIT_P107 "Tozasertib Lactate" @default.
- NCIT_C61319 NCIT_P108 "Tozasertib Lactate" @default.
- NCIT_C61319 NCIT_P207 "C1451033" @default.
- NCIT_C61319 NCIT_P210 "899827-04-4" @default.
- NCIT_C61319 NCIT_P319 "CN8EF9N084" @default.
- NCIT_C61319 NCIT_P322 "CTRP" @default.
- NCIT_C61319 NCIT_P322 "FDA" @default.
- NCIT_C61319 NCIT_P322 "GDC" @default.
- NCIT_C61319 NCIT_P329 "485305" @default.
- NCIT_C61319 NCIT_P330 "485305" @default.
- NCIT_C61319 NCIT_P350 "C23H28N8OS.C3H6O3" @default.
- NCIT_C61319 NCIT_P366 "MK-0457" @default.
- NCIT_C61319 NCIT_P375 "Tozasertib Lactate" @default.
- NCIT_C61319 NCIT_P399 "485305" @default.
- NCIT_C61319 NCIT_R146 NCIT_C16554 @default.
- NCIT_C61319 NCIT_R146 NCIT_C16984 @default.
- NCIT_C61319 NCIT_R146 NCIT_C17018 @default.
- NCIT_C61319 NCIT_R146 NCIT_C17021 @default.
- NCIT_C61319 NCIT_R146 NCIT_C17210 @default.
- NCIT_C61319 NCIT_R146 NCIT_C17325 @default.
- NCIT_C61319 NCIT_R146 NCIT_C20027 @default.
- NCIT_C61319 NCIT_R146 NCIT_C26548 @default.
- NCIT_C61319 NCIT_R146 NCIT_C30006 @default.
- NCIT_C61319 normalizedInformationContent "100" @default.
- NCIT_C61319 referenceCount "1" @default.
- NCIT_C61319 hasExactSynonym "Aurora Kinase Inhibitor MK-0457" @default.
- NCIT_C61319 hasExactSynonym "L-001281814" @default.
- NCIT_C61319 hasExactSynonym "MK-0457" @default.
- NCIT_C61319 hasExactSynonym "Propanoic acid, 2-hydroxy-, (2S)-, compd. with N-(4-((4-(4-methyl-1-piperazinyl)-6-((5-methyl-1H-pyrazol-3-yl)amino)-2-pyrimidinyl)thio)phenyl)cyclopropanecarboxamide" @default.
- NCIT_C61319 hasExactSynonym "TOZASERTIB LACTATE" @default.
- NCIT_C61319 hasExactSynonym "Tozasertib Lactate" @default.
- NCIT_C61319 hasExactSynonym "VX-680" @default.
- NCIT_C61319 inSubset NCIT_C116977 @default.
- NCIT_C61319 inSubset NCIT_C116978 @default.
- NCIT_C61319 inSubset NCIT_C128784 @default.
- NCIT_C61319 inSubset NCIT_C157711 @default.
- NCIT_C61319 inSubset NCIT_C157712 @default.
- NCIT_C61319 inSubset NCIT_C176424 @default.
- NCIT_C61319 inSubset NCIT_C177537 @default.
- NCIT_C61319 inSubset NCIT_C63923 @default.
- NCIT_C61319 type Class @default.
- NCIT_C61319 isDefinedBy ncit.owl @default.
- NCIT_C61319 label "Tozasertib Lactate" @default.
- NCIT_C61319 subClassOf NCIT_C129824 @default.
- NCIT_C61319 subClassOf NCIT_C129825 @default.
- NCIT_C61319 subClassOf NCIT_C1404 @default.
- NCIT_C61319 subClassOf NCIT_C1908 @default.
- NCIT_C61319 subClassOf NCIT_C1909 @default.
- NCIT_C61319 subClassOf NCIT_C2189 @default.
- NCIT_C61319 subClassOf NCIT_C274 @default.
- NCIT_C61319 subClassOf NCIT_C471 @default.
- NCIT_C61319 subClassOf NCIT_C61074 @default.
- NCIT_C61319 subClassOf NCIT_C61319 @default.
- NCIT_C61319 subClassOf NCIT_C62556 @default.