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- NCIT_C61568 IAO_0000115 "The hydrochloride salt of the anthracycline derivative berubicin with potential antineoplastic activity. Berubicin intercalates into DNA and interrupts topoisomerase II activity, resulting in the inhibition of DNA replication and repair, and RNA and protein synthesis. Unlike other anthracycline derivatives, this agent crosses the blood-brain barrier (BBB)." @default.
- NCIT_C61568 NCIT_A32 NCIT_C1909 @default.
- NCIT_C61568 NCIT_A6 NCIT_C83552 @default.
- NCIT_C61568 NCIT_A7 NCIT_C18434 @default.
- NCIT_C61568 NCIT_NHC0 "C61568" @default.
- NCIT_C61568 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C61568 NCIT_P107 "Berubicin Hydrochloride" @default.
- NCIT_C61568 NCIT_P108 "Berubicin Hydrochloride" @default.
- NCIT_C61568 NCIT_P208 "CL364772" @default.
- NCIT_C61568 NCIT_P210 "293736-67-1" @default.
- NCIT_C61568 NCIT_P319 "7BA3X03948" @default.
- NCIT_C61568 NCIT_P322 "CTRP" @default.
- NCIT_C61568 NCIT_P322 "FDA" @default.
- NCIT_C61568 NCIT_P322 "GDC" @default.
- NCIT_C61568 NCIT_P325 "A substance being studied in the treatment of adult brain tumors. RTA 744 crosses the blood-brain barrier and blocks an enzyme needed for cancer growth. It is a type of topoisomerase inhibitor." @default.
- NCIT_C61568 NCIT_P329 "491929" @default.
- NCIT_C61568 NCIT_P330 "491929" @default.
- NCIT_C61568 NCIT_P350 "C34H35NO11.HCl" @default.
- NCIT_C61568 NCIT_P366 "RTA_744" @default.
- NCIT_C61568 NCIT_P375 "Berubicin Hydrochloride" @default.
- NCIT_C61568 NCIT_P399 "491929" @default.
- NCIT_C61568 normalizedInformationContent "100" @default.
- NCIT_C61568 referenceCount "1" @default.
- NCIT_C61568 hasExactSynonym "(8S,10S)-10-((3-amino-4-O-benzyl-2,3,6-trideoxy-alpha-L-lyxo-hexopyranosyl)oxy)- 6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxy-7,8,9,10-tetrahydrotetracene-5,12-dione Hydrochloride" @default.
- NCIT_C61568 hasExactSynonym "BERUBICIN HYDROCHLORIDE" @default.
- NCIT_C61568 hasExactSynonym "Berubicin Hydrochloride" @default.
- NCIT_C61568 hasExactSynonym "RTA 744" @default.
- NCIT_C61568 hasExactSynonym "WP744" @default.
- NCIT_C61568 hasExactSynonym "topoisomerase II inhibitor RTA 744" @default.
- NCIT_C61568 inSubset NCIT_C116977 @default.
- NCIT_C61568 inSubset NCIT_C116978 @default.
- NCIT_C61568 inSubset NCIT_C128784 @default.
- NCIT_C61568 inSubset NCIT_C157711 @default.
- NCIT_C61568 inSubset NCIT_C157712 @default.
- NCIT_C61568 inSubset NCIT_C176424 @default.
- NCIT_C61568 inSubset NCIT_C177537 @default.
- NCIT_C61568 inSubset NCIT_C63923 @default.
- NCIT_C61568 type Class @default.
- NCIT_C61568 isDefinedBy ncit.owl @default.
- NCIT_C61568 label "Berubicin Hydrochloride" @default.
- NCIT_C61568 subClassOf NCIT_C129824 @default.
- NCIT_C61568 subClassOf NCIT_C129825 @default.
- NCIT_C61568 subClassOf NCIT_C1594 @default.
- NCIT_C61568 subClassOf NCIT_C1748 @default.
- NCIT_C61568 subClassOf NCIT_C186664 @default.
- NCIT_C61568 subClassOf NCIT_C1908 @default.
- NCIT_C61568 subClassOf NCIT_C1909 @default.
- NCIT_C61568 subClassOf NCIT_C1968 @default.
- NCIT_C61568 subClassOf NCIT_C2115 @default.
- NCIT_C61568 subClassOf NCIT_C2161 @default.
- NCIT_C61568 subClassOf NCIT_C2189 @default.
- NCIT_C61568 subClassOf NCIT_C259 @default.
- NCIT_C61568 subClassOf NCIT_C274 @default.
- NCIT_C61568 subClassOf NCIT_C2842 @default.
- NCIT_C61568 subClassOf NCIT_C471 @default.
- NCIT_C61568 subClassOf NCIT_C61568 @default.