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- NCIT_C61595 IAO_0000115 "A naturally occurring micronutrient, synthesized in small amounts by plants and animals (including humans), with antioxidant and potential chemopreventive activities. Alpha-lipoic acid acts as a free radical scavenger and assists in repairing oxidative damage and regenerates endogenous antioxidants, including vitamins C and E and glutathione. This agent also promotes glutathione synthesis. In addition, alpha-lipoic acid exerts metal chelating capacities and functions as a cofactor in various mitochondrial enzyme complexes involved in the decarboxylation of alpha-keto acids." @default.
- NCIT_C61595 NCIT_NHC0 "C61595" @default.
- NCIT_C61595 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C61595 NCIT_P107 "Alpha-Lipoic Acid" @default.
- NCIT_C61595 NCIT_P108 "Alpha-Lipoic Acid" @default.
- NCIT_C61595 NCIT_P207 "C2713339" @default.
- NCIT_C61595 NCIT_P210 "1077-28-7" @default.
- NCIT_C61595 NCIT_P319 "73Y7P0K73Y" @default.
- NCIT_C61595 NCIT_P322 "CTRP" @default.
- NCIT_C61595 NCIT_P322 "FDA" @default.
- NCIT_C61595 NCIT_P325 "A substance that is being studied for its ability to protect normal cells from the side effects of chemotherapy and prevent peripheral neuropathy (numbness, tingling, burning, and weakness in the hands or feet). Alpha-lipoic acid is made by the body and can be found in foods such as organ meats, spinach, broccoli, peas, brussel sprouts, and rice bran. It can also be made in the laboratory. Alpha-lipoic acid is a type of antioxidant and chemoprotective agent." @default.
- NCIT_C61595 NCIT_P329 "440740" @default.
- NCIT_C61595 NCIT_P330 "440740" @default.
- NCIT_C61595 NCIT_P350 "C8H14O2S2" @default.
- NCIT_C61595 NCIT_P366 "Alpha-Lipoic_Acid" @default.
- NCIT_C61595 NCIT_P368 "CHEBI:16494" @default.
- NCIT_C61595 NCIT_P399 "440740" @default.
- NCIT_C61595 normalizedInformationContent "100" @default.
- NCIT_C61595 referenceCount "1" @default.
- NCIT_C61595 hasExactSynonym "5-(1,2-Dithiolan-3-yl)pentanoic Acid" @default.
- NCIT_C61595 hasExactSynonym "6,8-Thioctic Acid" @default.
- NCIT_C61595 hasExactSynonym "ALPHA LIPOIC ACID" @default.
- NCIT_C61595 hasExactSynonym "Alpha-Lipoic Acid" @default.
- NCIT_C61595 hasExactSynonym "Lipoic Acid" @default.
- NCIT_C61595 hasExactSynonym "Thioctate" @default.
- NCIT_C61595 hasExactSynonym "Thioctic Acid" @default.
- NCIT_C61595 hasExactSynonym "alpha-lipoic acid" @default.
- NCIT_C61595 inSubset NCIT_C116977 @default.
- NCIT_C61595 inSubset NCIT_C116978 @default.
- NCIT_C61595 inSubset NCIT_C176424 @default.
- NCIT_C61595 inSubset NCIT_C63923 @default.
- NCIT_C61595 type Class @default.
- NCIT_C61595 isDefinedBy ncit.owl @default.
- NCIT_C61595 label "Alpha-Lipoic Acid" @default.
- NCIT_C61595 subClassOf NCIT_C1505 @default.
- NCIT_C61595 subClassOf NCIT_C1908 @default.
- NCIT_C61595 subClassOf NCIT_C1909 @default.
- NCIT_C61595 subClassOf NCIT_C26170 @default.
- NCIT_C61595 subClassOf NCIT_C275 @default.
- NCIT_C61595 subClassOf NCIT_C61595 @default.