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- NCIT_C61610 IAO_0000115 "A synthetic piperazine with anti-emetic, sedative and histamine H1antagonistic properties. Meclizine blocks the H1 histamine receptor and prevents the symptoms that are caused by histamine activity on capillaries, bronchial and gastrointestinal smooth muscles, including vasodilation, increased capillary permeability, bronchoconstriction, and spasmodic contraction of gastrointestinal smooth muscles. Meclizine hydrochloride may exert its antiemetic effects by its anticholinergic actions or due to a direct effect on the medullary chemoreceptive trigger zone." @default.
- NCIT_C61610 NCIT_A5 NCIT_C29245 @default.
- NCIT_C61610 NCIT_A5 NCIT_C77438 @default.
- NCIT_C61610 NCIT_NHC0 "C61610" @default.
- NCIT_C61610 NCIT_P106 "Organic Chemical" @default.
- NCIT_C61610 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C61610 NCIT_P107 "Meclizine" @default.
- NCIT_C61610 NCIT_P108 "Meclizine" @default.
- NCIT_C61610 NCIT_P207 "C0025039" @default.
- NCIT_C61610 NCIT_P210 "569-65-3" @default.
- NCIT_C61610 NCIT_P319 "3L5TQ84570" @default.
- NCIT_C61610 NCIT_P322 "CTRP" @default.
- NCIT_C61610 NCIT_P322 "FDA" @default.
- NCIT_C61610 NCIT_P350 "C25H27ClN2" @default.
- NCIT_C61610 NCIT_P366 "Meclizine" @default.
- NCIT_C61610 normalizedInformationContent "100" @default.
- NCIT_C61610 referenceCount "1" @default.
- NCIT_C61610 hasExactSynonym "1-[(4-Chlorophenyl)phenylmethyl]-4-[(3-methylphenyl)methyl]piperazine" @default.
- NCIT_C61610 hasExactSynonym "MECLIZINE" @default.
- NCIT_C61610 hasExactSynonym "Meclizine" @default.
- NCIT_C61610 hasExactSynonym "Meclozine" @default.
- NCIT_C61610 inSubset NCIT_C116977 @default.
- NCIT_C61610 inSubset NCIT_C116978 @default.
- NCIT_C61610 inSubset NCIT_C63923 @default.
- NCIT_C61610 type Class @default.
- NCIT_C61610 isDefinedBy ncit.owl @default.
- NCIT_C61610 label "Meclizine" @default.
- NCIT_C61610 subClassOf NCIT_C1908 @default.
- NCIT_C61610 subClassOf NCIT_C1909 @default.
- NCIT_C61610 subClassOf NCIT_C267 @default.
- NCIT_C61610 subClassOf NCIT_C29578 @default.
- NCIT_C61610 subClassOf NCIT_C308 @default.
- NCIT_C61610 subClassOf NCIT_C61610 @default.
- NCIT_C61610 subClassOf NCIT_C78272 @default.