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- NCIT_C61681 IAO_0000115 "A semisynthetic beta-lactamase inhibitor isolated from Streptomyces. Clavulanic acid contains a beta-lactam ring and binds strongly to beta-lactamase at or near its active site, thereby hindering enzymatic activity. This protects other beta-lactam antibiotics from beta-lactamase catalysis, thereby enhancing their antibacterial effects. This agent is used in conjunction with beta-lactamase susceptible antibiotics, such as penicillins and cephalosporins, to treat infections caused by beta-lactamase producing organisms." @default.
- NCIT_C61681 NCIT_A5 NCIT_C47453 @default.
- NCIT_C61681 NCIT_NHC0 "C61681" @default.
- NCIT_C61681 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C61681 NCIT_P107 "Clavulanic Acid" @default.
- NCIT_C61681 NCIT_P108 "Clavulanic Acid" @default.
- NCIT_C61681 NCIT_P207 "C0055860" @default.
- NCIT_C61681 NCIT_P210 "58001-44-8" @default.
- NCIT_C61681 NCIT_P319 "23521W1S24" @default.
- NCIT_C61681 NCIT_P322 "CTRP" @default.
- NCIT_C61681 NCIT_P322 "FDA" @default.
- NCIT_C61681 NCIT_P350 "C8H9NO5" @default.
- NCIT_C61681 NCIT_P366 "Clavulanic_Acid" @default.
- NCIT_C61681 NCIT_P368 "CHEBI:48947" @default.
- NCIT_C61681 NCIT_P399 "813341" @default.
- NCIT_C61681 normalizedInformationContent "100" @default.
- NCIT_C61681 referenceCount "1" @default.
- NCIT_C61681 hasExactSynonym "(Z)-(2R,5R)-3-(2-Hydroxyethylidene)-7-oxo-4-oxa-1-azabicyclo(3.2.0)heptane-2-carboxylic acid" @default.
- NCIT_C61681 hasExactSynonym "Antibiotic MM 14151" @default.
- NCIT_C61681 hasExactSynonym "CLAVULANIC ACID" @default.
- NCIT_C61681 hasExactSynonym "Clavulanic Acid" @default.
- NCIT_C61681 inSubset NCIT_C116977 @default.
- NCIT_C61681 inSubset NCIT_C116978 @default.
- NCIT_C61681 inSubset NCIT_C63923 @default.
- NCIT_C61681 type Class @default.
- NCIT_C61681 isDefinedBy ncit.owl @default.
- NCIT_C61681 label "Clavulanic Acid" @default.
- NCIT_C61681 subClassOf NCIT_C183118 @default.
- NCIT_C61681 subClassOf NCIT_C1908 @default.
- NCIT_C61681 subClassOf NCIT_C1909 @default.
- NCIT_C61681 subClassOf NCIT_C2140 @default.
- NCIT_C61681 subClassOf NCIT_C61681 @default.