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- NCIT_C617 IAO_0000115 "A nitrosourea with antineoplastic activity. Lomustine alkylates and crosslinks DNA, thereby inhibiting DNA and RNA synthesis. This agent also carbamoylates DNA and proteins, resulting in inhibition of DNA and RNA synthesis and disruption of RNA processing. Lomustine is lipophilic and crosses the blood-brain barrier. (NCI04)" @default.
- NCIT_C617 NCIT_A32 NCIT_C1909 @default.
- NCIT_C617 NCIT_NHC0 "C617" @default.
- NCIT_C617 NCIT_P106 "Organic Chemical" @default.
- NCIT_C617 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C617 NCIT_P107 "Lomustine" @default.
- NCIT_C617 NCIT_P108 "Lomustine" @default.
- NCIT_C617 NCIT_P175 "79037" @default.
- NCIT_C617 NCIT_P207 "C0023972" @default.
- NCIT_C617 NCIT_P210 "13010-47-4" @default.
- NCIT_C617 NCIT_P302 "Brain tumors; Hodgkins disease" @default.
- NCIT_C617 NCIT_P319 "7BRF0Z81KG" @default.
- NCIT_C617 NCIT_P322 "CTRP" @default.
- NCIT_C617 NCIT_P322 "FDA" @default.
- NCIT_C617 NCIT_P322 "GDC" @default.
- NCIT_C617 NCIT_P325 "An anticancer drug that belongs to the family of drugs called alkylating agents." @default.
- NCIT_C617 NCIT_P329 "43065" @default.
- NCIT_C617 NCIT_P330 "43065" @default.
- NCIT_C617 NCIT_P350 "C9H16ClN3O2" @default.
- NCIT_C617 NCIT_P366 "Lomustine" @default.
- NCIT_C617 NCIT_P375 "Lomustine" @default.
- NCIT_C617 NCIT_P399 "43065" @default.
- NCIT_C617 normalizedInformationContent "71.700606907059111" @default.
- NCIT_C617 referenceCount "72" @default.
- NCIT_C617 hasExactSynonym "1-(2-Chloroethyl)-3-cyclohexyl-1-nitrosourea" @default.
- NCIT_C617 hasExactSynonym "1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea" @default.
- NCIT_C617 hasExactSynonym "1-Nitrosourea, 1-(2-chloroethyl)-3-cyclohexyl-" @default.
- NCIT_C617 hasExactSynonym "Belustin" @default.
- NCIT_C617 hasExactSynonym "Belustine" @default.
- NCIT_C617 hasExactSynonym "CCNU" @default.
- NCIT_C617 hasExactSynonym "Cecenu" @default.
- NCIT_C617 hasExactSynonym "CeeNU" @default.
- NCIT_C617 hasExactSynonym "Chloroethylcyclo- hexylnitrosourea" @default.
- NCIT_C617 hasExactSynonym "Chloroethylcyclohexylnitrosourea" @default.
- NCIT_C617 hasExactSynonym "Citostal" @default.
- NCIT_C617 hasExactSynonym "Gleostine" @default.
- NCIT_C617 hasExactSynonym "LOMUSTINE" @default.
- NCIT_C617 hasExactSynonym "Lomeblastin" @default.
- NCIT_C617 hasExactSynonym "Lomustine" @default.
- NCIT_C617 hasExactSynonym "Lomustinum" @default.
- NCIT_C617 hasExactSynonym "Lucostin" @default.
- NCIT_C617 hasExactSynonym "Lucostine" @default.
- NCIT_C617 hasExactSynonym "N-(2-Chloroethyl)-N'-cyclohexyl-N-nitrosourea" @default.
- NCIT_C617 hasExactSynonym "N-(2-chloroethyl)-N'-cyclohexyl-N-nitrosourea" @default.
- NCIT_C617 hasExactSynonym "Prava" @default.
- NCIT_C617 hasExactSynonym "RB-1509" @default.
- NCIT_C617 hasExactSynonym "WR-139017" @default.
- NCIT_C617 hasExactSynonym "lomustine" @default.
- NCIT_C617 inSubset NCIT_C116977 @default.
- NCIT_C617 inSubset NCIT_C116978 @default.
- NCIT_C617 inSubset NCIT_C128784 @default.
- NCIT_C617 inSubset NCIT_C157711 @default.
- NCIT_C617 inSubset NCIT_C157712 @default.
- NCIT_C617 inSubset NCIT_C176424 @default.
- NCIT_C617 inSubset NCIT_C177537 @default.
- NCIT_C617 inSubset NCIT_C63923 @default.
- NCIT_C617 type Class @default.
- NCIT_C617 isDefinedBy ncit.owl @default.
- NCIT_C617 label "Lomustine" @default.
- NCIT_C617 subClassOf NCIT_C1590 @default.
- NCIT_C617 subClassOf NCIT_C186664 @default.
- NCIT_C617 subClassOf NCIT_C1908 @default.
- NCIT_C617 subClassOf NCIT_C1909 @default.
- NCIT_C617 subClassOf NCIT_C274 @default.
- NCIT_C617 subClassOf NCIT_C2842 @default.
- NCIT_C617 subClassOf NCIT_C617 @default.
- NCIT_C617 subClassOf NCIT_C699 @default.