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- NCIT_C61739 IAO_0000115 "A non-essential amino acid and dextro isomer of serine with antipsychotic activity. D-serine is a selective full agonist at the glycine site of N-methyl-D-aspartate (NMDA)-type glutamate receptor. Hypofunction of NMDA type of neurotransmission is believed to play a major role in pathophysiology of schizophrenia, therefore, administration of D-serine and subsequent activation of NMDA receptors may alleviate psychotic tendencies." @default.
- NCIT_C61739 NCIT_NHC0 "C61739" @default.
- NCIT_C61739 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C61739 NCIT_P108 "D-Serine" @default.
- NCIT_C61739 NCIT_P175 "77689" @default.
- NCIT_C61739 NCIT_P207 "C1880218" @default.
- NCIT_C61739 NCIT_P210 "312-84-5" @default.
- NCIT_C61739 NCIT_P319 "1K77H2Z9B1" @default.
- NCIT_C61739 NCIT_P322 "FDA" @default.
- NCIT_C61739 NCIT_P350 "C3H7NO3" @default.
- NCIT_C61739 NCIT_P366 "D-Serine" @default.
- NCIT_C61739 NCIT_P368 "CHEBI:16523" @default.
- NCIT_C61739 normalizedInformationContent "100" @default.
- NCIT_C61739 referenceCount "1" @default.
- NCIT_C61739 hasExactSynonym "D-Serine" @default.
- NCIT_C61739 hasExactSynonym "SERINE, D-" @default.
- NCIT_C61739 inSubset NCIT_C63923 @default.
- NCIT_C61739 type Class @default.
- NCIT_C61739 isDefinedBy ncit.owl @default.
- NCIT_C61739 label "D-Serine" @default.
- NCIT_C61739 subClassOf NCIT_C1908 @default.
- NCIT_C61739 subClassOf NCIT_C1913 @default.
- NCIT_C61739 subClassOf NCIT_C200714 @default.
- NCIT_C61739 subClassOf NCIT_C231 @default.
- NCIT_C61739 subClassOf NCIT_C232 @default.
- NCIT_C61739 subClassOf NCIT_C29596 @default.
- NCIT_C61739 subClassOf NCIT_C61739 @default.
- NCIT_C61739 subClassOf NCIT_C718 @default.