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- NCIT_C61745 IAO_0000115 "The orally bioavailable citrate salt of enclomiphene, the trans-isomer of the nonsteroidal triphenylethylene compound clomiphene, with tissue-selective estrogenic and antiestrogenic activities. As a selective estrogen receptor modulator (SERM), enclomiphene binds to hypothalamic estrogen receptors, blocking the negative feedback of endogenous estrogens and stimulating the release of gonadotropin-releasing hormone (GnRH) from the hypothalamus; released GnRH subsequently stimulates the release of follicle-stimulating hormone (FSH) and luteinizing hormone (LH) from the anterior pituitary, resulting in ovulation. In addition, this agent may bind to estrogen receptors on breast cancer cells, resulting in the inhibition of estrogen-stimulated proliferation in susceptible cell populations." @default.
- NCIT_C61745 NCIT_A32 NCIT_C1909 @default.
- NCIT_C61745 NCIT_A6 NCIT_C28211 @default.
- NCIT_C61745 NCIT_NHC0 "C61745" @default.
- NCIT_C61745 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C61745 NCIT_P108 "Enclomiphene Citrate" @default.
- NCIT_C61745 NCIT_P207 "C0086214" @default.
- NCIT_C61745 NCIT_P210 "7599-79-3" @default.
- NCIT_C61745 NCIT_P319 "J303A6U9Y6" @default.
- NCIT_C61745 NCIT_P322 "FDA" @default.
- NCIT_C61745 NCIT_P322 "GDC" @default.
- NCIT_C61745 NCIT_P329 "39307" @default.
- NCIT_C61745 NCIT_P330 "39307" @default.
- NCIT_C61745 NCIT_P350 "C26H28ClNO.C6H8O7" @default.
- NCIT_C61745 NCIT_P366 "Enclomiphene_Citrate" @default.
- NCIT_C61745 NCIT_P375 "Enclomiphene Citrate" @default.
- NCIT_C61745 NCIT_P399 "39307" @default.
- NCIT_C61745 normalizedInformationContent "100" @default.
- NCIT_C61745 referenceCount "1" @default.
- NCIT_C61745 hasExactSynonym "Androxal" @default.
- NCIT_C61745 hasExactSynonym "ENCLOMIPHENE CITRATE" @default.
- NCIT_C61745 hasExactSynonym "Enclomiphene Citrate" @default.
- NCIT_C61745 inSubset NCIT_C128784 @default.
- NCIT_C61745 inSubset NCIT_C157711 @default.
- NCIT_C61745 inSubset NCIT_C157712 @default.
- NCIT_C61745 inSubset NCIT_C176424 @default.
- NCIT_C61745 inSubset NCIT_C177537 @default.
- NCIT_C61745 inSubset NCIT_C63923 @default.
- NCIT_C61745 type Class @default.
- NCIT_C61745 isDefinedBy ncit.owl @default.
- NCIT_C61745 label "Enclomiphene Citrate" @default.
- NCIT_C61745 subClassOf NCIT_C129818 @default.
- NCIT_C61745 subClassOf NCIT_C147908 @default.
- NCIT_C61745 subClassOf NCIT_C163758 @default.
- NCIT_C61745 subClassOf NCIT_C1821 @default.
- NCIT_C61745 subClassOf NCIT_C1892 @default.
- NCIT_C61745 subClassOf NCIT_C1908 @default.
- NCIT_C61745 subClassOf NCIT_C1909 @default.
- NCIT_C61745 subClassOf NCIT_C274 @default.
- NCIT_C61745 subClassOf NCIT_C481 @default.
- NCIT_C61745 subClassOf NCIT_C483 @default.
- NCIT_C61745 subClassOf NCIT_C547 @default.
- NCIT_C61745 subClassOf NCIT_C548 @default.
- NCIT_C61745 subClassOf NCIT_C61745 @default.