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- NCIT_C61797 IAO_0000115 "A cyclohexanone derivative with analgesic and anesthetic properties. Although its mechanism of action is not well understood, ketamine appears exerts complex pharmacological actions including inhibition of biogenic amine uptake, binding to opioid receptors, and inhibition of N-methyl D-aspartate (NMDA) receptors. Because of the involvement of spinal NMDA receptors in the process of central sensitization, this agent may reduce pain perception and induce sedation." @default.
- NCIT_C61797 NCIT_A5 NCIT_C29142 @default.
- NCIT_C61797 NCIT_NHC0 "C61797" @default.
- NCIT_C61797 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C61797 NCIT_P107 "Ketamine" @default.
- NCIT_C61797 NCIT_P108 "Ketamine" @default.
- NCIT_C61797 NCIT_P207 "C0022614" @default.
- NCIT_C61797 NCIT_P210 "6740-88-1" @default.
- NCIT_C61797 NCIT_P319 "690G0D6V8H" @default.
- NCIT_C61797 NCIT_P322 "CTRP" @default.
- NCIT_C61797 NCIT_P322 "FDA" @default.
- NCIT_C61797 NCIT_P325 "A drug used to cause a loss of feeling and awareness and to induce sleep in patients having surgery. It is also being studied in the treatment of nerve pain caused by chemotherapy. Ketamine blocks pathways to the brain that are involved in sensing pain. It is a type of general anesthetic." @default.
- NCIT_C61797 NCIT_P350 "C13H16ClNO" @default.
- NCIT_C61797 NCIT_P366 "Ketamine" @default.
- NCIT_C61797 NCIT_P368 "CHEBI:6121" @default.
- NCIT_C61797 normalizedInformationContent "100" @default.
- NCIT_C61797 referenceCount "1" @default.
- NCIT_C61797 hasExactSynonym "KETAMINE" @default.
- NCIT_C61797 hasExactSynonym "Ketamine" @default.
- NCIT_C61797 hasExactSynonym "ketamine" @default.
- NCIT_C61797 inSubset NCIT_C116977 @default.
- NCIT_C61797 inSubset NCIT_C116978 @default.
- NCIT_C61797 inSubset NCIT_C173381 @default.
- NCIT_C61797 inSubset NCIT_C173383 @default.
- NCIT_C61797 inSubset NCIT_C63923 @default.
- NCIT_C61797 type Class @default.
- NCIT_C61797 isDefinedBy ncit.owl @default.
- NCIT_C61797 label "Ketamine" @default.
- NCIT_C61797 subClassOf NCIT_C1908 @default.
- NCIT_C61797 subClassOf NCIT_C1909 @default.
- NCIT_C61797 subClassOf NCIT_C245 @default.
- NCIT_C61797 subClassOf NCIT_C61797 @default.
- NCIT_C61797 subClassOf NCIT_C78272 @default.