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- NCIT_C61803 IAO_0000115 "The anhydrous, levorotatory isomer of a synthetic hydrazine derivative of the neurotransmitter dopamine. Carbidopa, a peripheral dopa decarboxylase inhibitor, is used as an adjunct with levodopa to prevent levodopa degradation to dopamine in extracerebral tissue, thereby decreasing the peripheral side effects of levodopa. Carbidopa does not penetrate the blood brain barrier; therefore, it does not interfere with the central nervous system (CNS) metabolism of levodopa to the active neurotransmitter dopamine which, in high concentrations in the brain, has anti-parkinsonian effects." @default.
- NCIT_C61803 NCIT_NHC0 "C61803" @default.
- NCIT_C61803 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C61803 NCIT_P108 "Carbidopa Anhydrous" @default.
- NCIT_C61803 NCIT_P207 "C1881339" @default.
- NCIT_C61803 NCIT_P210 "28860-95-9" @default.
- NCIT_C61803 NCIT_P319 "KR87B45RGH" @default.
- NCIT_C61803 NCIT_P322 "FDA" @default.
- NCIT_C61803 NCIT_P350 "C10H14N2O4" @default.
- NCIT_C61803 NCIT_P366 "L-Carbidopa_Anhydrous" @default.
- NCIT_C61803 NCIT_P368 "CHEBI:39585" @default.
- NCIT_C61803 normalizedInformationContent "100" @default.
- NCIT_C61803 referenceCount "1" @default.
- NCIT_C61803 hasExactSynonym "Benzenepropanoic Acid, alpha-hydrazino-3,4-Dihydroxy-alpha-methyl-, (S)-" @default.
- NCIT_C61803 hasExactSynonym "CARBIDOPA ANHYDROUS" @default.
- NCIT_C61803 hasExactSynonym "Carbidopa Anhydrous" @default.
- NCIT_C61803 hasExactSynonym "L-Carbidopa Anhydrous" @default.
- NCIT_C61803 inSubset NCIT_C63923 @default.
- NCIT_C61803 type Class @default.
- NCIT_C61803 isDefinedBy ncit.owl @default.
- NCIT_C61803 label "Carbidopa Anhydrous" @default.
- NCIT_C61803 subClassOf NCIT_C1908 @default.
- NCIT_C61803 subClassOf NCIT_C1909 @default.
- NCIT_C61803 subClassOf NCIT_C38149 @default.
- NCIT_C61803 subClassOf NCIT_C61803 @default.
- NCIT_C61803 subClassOf NCIT_C66884 @default.
- NCIT_C61803 subClassOf NCIT_C78272 @default.