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- NCIT_C61867 IAO_0000115 "The hydrochloride salt form of olopatadine, a dual action selective histamine H1 receptor antagonist and mast cell stabilizer with anti-allergic activity. Olopatadine stabilizes mast cells and prevents histamine release from mast cells. In addition, this agent also blocks histamine H1 receptors, thereby preventing histamine from binding to these receptors. Both actions prevent the effects of histamine on capillaries, bronchial smooth muscle, and gastrointestinal (GI) smooth muscle, including histamine-induced vasodilation, increased capillary permeability, bronchoconstriction, and spasmodic contraction of GI smooth muscle. This drug also prevents histamine-induced pain and itching of mucous membranes." @default.
- NCIT_C61867 NCIT_A6 NCIT_C61866 @default.
- NCIT_C61867 NCIT_NHC0 "C61867" @default.
- NCIT_C61867 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C61867 NCIT_P108 "Olopatadine Hydrochloride" @default.
- NCIT_C61867 NCIT_P207 "C0771892" @default.
- NCIT_C61867 NCIT_P210 "140462-76-6" @default.
- NCIT_C61867 NCIT_P319 "2XG66W44KF" @default.
- NCIT_C61867 NCIT_P322 "FDA" @default.
- NCIT_C61867 NCIT_P350 "C21H23NO3.HCl" @default.
- NCIT_C61867 NCIT_P366 "Olopatadine_Hydrochloride" @default.
- NCIT_C61867 normalizedInformationContent "100" @default.
- NCIT_C61867 referenceCount "1" @default.
- NCIT_C61867 hasExactSynonym "ALO-4943A" @default.
- NCIT_C61867 hasExactSynonym "Dibenz[B,E]Oxepin-2-Acetic Acid, 11-[3-(Dimethylamino)Propylidene]-6,11-Dihydro-, Hydrochloride, (Z)-" @default.
- NCIT_C61867 hasExactSynonym "KW-4679" @default.
- NCIT_C61867 hasExactSynonym "OLOPATADINE HYDROCHLORIDE" @default.
- NCIT_C61867 hasExactSynonym "Olopatadine Hydrochloride" @default.
- NCIT_C61867 hasExactSynonym "Pataday" @default.
- NCIT_C61867 hasExactSynonym "Patanase" @default.
- NCIT_C61867 hasExactSynonym "Patanol" @default.
- NCIT_C61867 inSubset NCIT_C63923 @default.
- NCIT_C61867 type Class @default.
- NCIT_C61867 isDefinedBy ncit.owl @default.
- NCIT_C61867 label "Olopatadine Hydrochloride" @default.
- NCIT_C61867 subClassOf NCIT_C1908 @default.
- NCIT_C61867 subClassOf NCIT_C1909 @default.
- NCIT_C61867 subClassOf NCIT_C29578 @default.
- NCIT_C61867 subClassOf NCIT_C308 @default.
- NCIT_C61867 subClassOf NCIT_C61867 @default.