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- NCIT_C61877 IAO_0000115 "The sodium salt form of a substituted benzimidazole with proton pump inhibitor activity. Pantoprazole is a lipophilic, weak base that crosses the parietal cell membrane and enters the acidic parietal cell canaliculus where it becomes protonated, producing the active metabolite sulfenamide, which forms an irreversible covalent bond with two sites of the H+/K+-ATPase enzyme located on the gastric parietal cell, thereby inhibiting both basal and stimulated gastric acid production." @default.
- NCIT_C61877 NCIT_A6 NCIT_C29346 @default.
- NCIT_C61877 NCIT_NHC0 "C61877" @default.
- NCIT_C61877 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C61877 NCIT_P108 "Pantoprazole Sodium" @default.
- NCIT_C61877 NCIT_P207 "C0795650" @default.
- NCIT_C61877 NCIT_P210 "164579-32-2" @default.
- NCIT_C61877 NCIT_P302 "Gastroesophageal Reflux Disease" @default.
- NCIT_C61877 NCIT_P319 "6871619Q5X" @default.
- NCIT_C61877 NCIT_P322 "FDA" @default.
- NCIT_C61877 NCIT_P329 "682170" @default.
- NCIT_C61877 NCIT_P330 "682170" @default.
- NCIT_C61877 NCIT_P350 "2C16H14F2N3O4S.2Na.3H2O" @default.
- NCIT_C61877 NCIT_P366 "Pantoprazole_Sodium" @default.
- NCIT_C61877 NCIT_P368 "CHEBI:50270" @default.
- NCIT_C61877 NCIT_P399 "682170" @default.
- NCIT_C61877 normalizedInformationContent "100" @default.
- NCIT_C61877 referenceCount "1" @default.
- NCIT_C61877 hasExactSynonym "PANTOPRAZOLE SODIUM" @default.
- NCIT_C61877 hasExactSynonym "Pantoprazole Sodium" @default.
- NCIT_C61877 hasExactSynonym "Protonix" @default.
- NCIT_C61877 inSubset NCIT_C176424 @default.
- NCIT_C61877 inSubset NCIT_C63923 @default.
- NCIT_C61877 type Class @default.
- NCIT_C61877 isDefinedBy ncit.owl @default.
- NCIT_C61877 label "Pantoprazole Sodium" @default.
- NCIT_C61877 subClassOf NCIT_C1908 @default.
- NCIT_C61877 subClassOf NCIT_C1909 @default.
- NCIT_C61877 subClassOf NCIT_C29701 @default.
- NCIT_C61877 subClassOf NCIT_C29723 @default.
- NCIT_C61877 subClassOf NCIT_C61877 @default.
- NCIT_C61877 subClassOf NCIT_C78276 @default.