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- NCIT_C61893 IAO_0000115 "A short-acting, beta-adrenergic receptor agonist with bronchodilator activity. Pirbuterol selectively binds to beta-2 adrenergic receptors in bronchial smooth muscle, thereby activating intracellular adenyl cyclase, an enzyme that catalyzes the conversion of adenosine triphosphate (ATP) to cyclic-3',5'-adenosine monophosphate (cAMP). Increased cAMP levels cause relaxation of bronchial smooth muscle, relieve bronchospasms, improve mucociliary clearance and inhibit the release of mediators of immediate hypersensitivity from cells, especially from mast cells." @default.
- NCIT_C61893 NCIT_A5 NCIT_C47675 @default.
- NCIT_C61893 NCIT_A5 NCIT_C76545 @default.
- NCIT_C61893 NCIT_NHC0 "C61893" @default.
- NCIT_C61893 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C61893 NCIT_P108 "Pirbuterol" @default.
- NCIT_C61893 NCIT_P207 "C0071129" @default.
- NCIT_C61893 NCIT_P210 "38677-81-5" @default.
- NCIT_C61893 NCIT_P319 "OG645J8RVW" @default.
- NCIT_C61893 NCIT_P322 "FDA" @default.
- NCIT_C61893 NCIT_P350 "C12H20N2O3" @default.
- NCIT_C61893 NCIT_P366 "Pirbuterol" @default.
- NCIT_C61893 normalizedInformationContent "100" @default.
- NCIT_C61893 referenceCount "1" @default.
- NCIT_C61893 hasExactSynonym "PIRBUTEROL" @default.
- NCIT_C61893 hasExactSynonym "Pirbuterol" @default.
- NCIT_C61893 inSubset NCIT_C63923 @default.
- NCIT_C61893 type Class @default.
- NCIT_C61893 isDefinedBy ncit.owl @default.
- NCIT_C61893 label "Pirbuterol" @default.
- NCIT_C61893 subClassOf NCIT_C1908 @default.
- NCIT_C61893 subClassOf NCIT_C1909 @default.
- NCIT_C61893 subClassOf NCIT_C29712 @default.
- NCIT_C61893 subClassOf NCIT_C29747 @default.
- NCIT_C61893 subClassOf NCIT_C319 @default.
- NCIT_C61893 subClassOf NCIT_C48149 @default.
- NCIT_C61893 subClassOf NCIT_C61893 @default.
- NCIT_C61893 subClassOf NCIT_C78272 @default.
- NCIT_C61893 subClassOf NCIT_C78273 @default.
- NCIT_C61893 subClassOf NCIT_C87053 @default.