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- NCIT_C61903 IAO_0000115 "A morpholine derivative with local anesthetic property. Pramocaine decreases the permeability of the neuronal membrane to sodium ions by reversibly binding to and inhibiting voltage-gated sodium channels. This results in stabilization of the membrane and, thereby inhibiting the ionic fluxes required for membrane depolarization, hence resulting in the failure to initiate a propagated action potential and subsequent conduction blockade." @default.
- NCIT_C61903 NCIT_A5 NCIT_C47682 @default.
- NCIT_C61903 NCIT_NHC0 "C61903" @default.
- NCIT_C61903 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C61903 NCIT_P108 "Pramocaine" @default.
- NCIT_C61903 NCIT_P207 "C0071810" @default.
- NCIT_C61903 NCIT_P210 "140-65-8" @default.
- NCIT_C61903 NCIT_P319 "068X84E056" @default.
- NCIT_C61903 NCIT_P322 "FDA" @default.
- NCIT_C61903 NCIT_P350 "C17H27NO3" @default.
- NCIT_C61903 NCIT_P366 "Pramoxine" @default.
- NCIT_C61903 NCIT_P368 "CHEBI:8357" @default.
- NCIT_C61903 normalizedInformationContent "100" @default.
- NCIT_C61903 referenceCount "1" @default.
- NCIT_C61903 hasExactSynonym "4-(3-(p-Butoxyphenoxy)propyl)morpholine" @default.
- NCIT_C61903 hasExactSynonym "PRAMOXINE" @default.
- NCIT_C61903 hasExactSynonym "Pramocaine" @default.
- NCIT_C61903 hasExactSynonym "Pramoxine" @default.
- NCIT_C61903 inSubset NCIT_C63923 @default.
- NCIT_C61903 type Class @default.
- NCIT_C61903 isDefinedBy ncit.owl @default.
- NCIT_C61903 label "Pramocaine" @default.
- NCIT_C61903 subClassOf NCIT_C1908 @default.
- NCIT_C61903 subClassOf NCIT_C1909 @default.
- NCIT_C61903 subClassOf NCIT_C245 @default.
- NCIT_C61903 subClassOf NCIT_C61903 @default.
- NCIT_C61903 subClassOf NCIT_C78272 @default.