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- NCIT_C61952 IAO_0000115 "An aminoglycoside antibiotic derived from Streptomyces griseus with antibacterial activity. Streptomycin irreversibly binds to the 16S rRNA and S12 protein within the bacterial 30S ribosomal subunit. As a result, this agent interferes with the assembly of initiation complex between mRNA and the bacterial ribosome, thereby inhibiting the initiation of protein synthesis. In addition, streptomycin induces misreading of the mRNA template and causes translational frameshift, thereby results in premature termination. This eventually leads to bacterial cell death." @default.
- NCIT_C61952 NCIT_A5 NCIT_C47729 @default.
- NCIT_C61952 NCIT_NHC0 "C61952" @default.
- NCIT_C61952 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C61952 NCIT_P108 "Streptomycin" @default.
- NCIT_C61952 NCIT_P207 "C0038425" @default.
- NCIT_C61952 NCIT_P210 "57-92-1" @default.
- NCIT_C61952 NCIT_P319 "Y45QSO73OB" @default.
- NCIT_C61952 NCIT_P322 "FDA" @default.
- NCIT_C61952 NCIT_P350 "C21H39N7O12" @default.
- NCIT_C61952 NCIT_P366 "Streptomycin" @default.
- NCIT_C61952 NCIT_P368 "CHEBI:17076" @default.
- NCIT_C61952 normalizedInformationContent "100" @default.
- NCIT_C61952 referenceCount "1" @default.
- NCIT_C61952 hasExactSynonym "STREPTOMYCIN" @default.
- NCIT_C61952 hasExactSynonym "Streptomycin" @default.
- NCIT_C61952 inSubset NCIT_C63923 @default.
- NCIT_C61952 type Class @default.
- NCIT_C61952 isDefinedBy ncit.owl @default.
- NCIT_C61952 label "Streptomycin" @default.
- NCIT_C61952 subClassOf NCIT_C1908 @default.
- NCIT_C61952 subClassOf NCIT_C1909 @default.
- NCIT_C61952 subClassOf NCIT_C2363 @default.
- NCIT_C61952 subClassOf NCIT_C254 @default.
- NCIT_C61952 subClassOf NCIT_C258 @default.
- NCIT_C61952 subClassOf NCIT_C61952 @default.
- NCIT_C61952 subClassOf NCIT_C784 @default.