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- NCIT_C61957 IAO_0000115 "A semi-synthetic beta-lactamase inhibitor. The beta-lactam ring of sulbactam irreversibly binds to beta-lactamase at or near its active site, thereby blocking enzyme activity and preventing metabolism of other beta-lactam antibiotics by the enzyme. Combining this agent with a beta-lactamase susceptible antibiotic, such as penicillins or a cephalosporin, to treat infections caused by beta-lactamase producing organisms, results in a decreased turnover rate of the beta-lactamase sensitive antibiotic and enhances its antibacterial activity." @default.
- NCIT_C61957 NCIT_A5 NCIT_C47732 @default.
- NCIT_C61957 NCIT_NHC0 "C61957" @default.
- NCIT_C61957 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C61957 NCIT_P108 "Sulbactam" @default.
- NCIT_C61957 NCIT_P207 "C0038665" @default.
- NCIT_C61957 NCIT_P210 "68373-14-8" @default.
- NCIT_C61957 NCIT_P319 "S4TF6I2330" @default.
- NCIT_C61957 NCIT_P322 "FDA" @default.
- NCIT_C61957 NCIT_P350 "C8H11NO5S" @default.
- NCIT_C61957 NCIT_P366 "Sulbactam" @default.
- NCIT_C61957 NCIT_P368 "CHEBI:9321" @default.
- NCIT_C61957 normalizedInformationContent "100" @default.
- NCIT_C61957 referenceCount "1" @default.
- NCIT_C61957 hasExactSynonym "(2S,5R)-3,3-Dimethyl-7-oxo-4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylic Acid 4,4-dioxide" @default.
- NCIT_C61957 hasExactSynonym "CP 45899" @default.
- NCIT_C61957 hasExactSynonym "SULBACTAM" @default.
- NCIT_C61957 hasExactSynonym "Sulbactam" @default.
- NCIT_C61957 inSubset NCIT_C63923 @default.
- NCIT_C61957 type Class @default.
- NCIT_C61957 isDefinedBy ncit.owl @default.
- NCIT_C61957 label "Sulbactam" @default.
- NCIT_C61957 subClassOf NCIT_C183118 @default.
- NCIT_C61957 subClassOf NCIT_C1908 @default.
- NCIT_C61957 subClassOf NCIT_C1909 @default.
- NCIT_C61957 subClassOf NCIT_C2140 @default.
- NCIT_C61957 subClassOf NCIT_C61957 @default.