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- NCIT_C62025 IAO_0000115 "A monoamine compound with positive inotropic activity. Dopamine is a naturally occurring catecholamine formed by decarboxylation of dehydroxyphenylalanine and a precursor of norepinephrine and epinephrine. Dopamine binds to alpha-1 and beta-1 adrenergic receptors. Mediated through myocardial beta-1 adrenergic receptors, dopamine increase heart rate and force, thereby increasing cardiac output. Alpha-1 adrenergic receptor stimulation on vascular smooth muscle, leads to vasoconstriction and results in an increase in systemic vascular resistance. Stimulation of dopaminergic receptors in renal vasculature, leads to renal blood vessel dilation, and an increase in glomerular filtration rate, renal blood flow, sodium excretion, and urine output." @default.
- NCIT_C62025 NCIT_A5 NCIT_C455 @default.
- NCIT_C62025 NCIT_NHC0 "C62025" @default.
- NCIT_C62025 NCIT_P106 "Biologically Active Substance" @default.
- NCIT_C62025 NCIT_P108 "Dopamine" @default.
- NCIT_C62025 NCIT_P207 "C0013030" @default.
- NCIT_C62025 NCIT_P210 "51-61-6" @default.
- NCIT_C62025 NCIT_P319 "VTD58H1Z2X" @default.
- NCIT_C62025 NCIT_P322 "FDA" @default.
- NCIT_C62025 NCIT_P350 "C8H11NO2" @default.
- NCIT_C62025 NCIT_P366 "Dopamine_Base" @default.
- NCIT_C62025 NCIT_P368 "CHEBI:18243" @default.
- NCIT_C62025 normalizedInformationContent "100" @default.
- NCIT_C62025 referenceCount "1" @default.
- NCIT_C62025 hasExactSynonym "DOPAMINE" @default.
- NCIT_C62025 hasExactSynonym "Dopamine" @default.
- NCIT_C62025 inSubset NCIT_C63923 @default.
- NCIT_C62025 type Class @default.
- NCIT_C62025 isDefinedBy ncit.owl @default.
- NCIT_C62025 label "Dopamine" @default.
- NCIT_C62025 subClassOf NCIT_C1899 @default.
- NCIT_C62025 subClassOf NCIT_C1908 @default.
- NCIT_C62025 subClassOf NCIT_C2315 @default.
- NCIT_C62025 subClassOf NCIT_C62025 @default.
- NCIT_C62025 subClassOf NCIT_C687 @default.
- NCIT_C62025 subClassOf NCIT_C88516 @default.