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- NCIT_C62054 IAO_0000115 "A thebaine derivate with competitive opioid antagonistic properties. Naloxone reverses the effects of opioid analgesics by binding to the opioid receptors in the CNS, and inhibiting the typical actions of opioid analgesics, including analgesia, euphoria, sedation, respiratory depression, miosis, bradycardia, and physical dependence. Naloxone binds to mu-opioid receptors with a high affinity, and a lesser degree to kappa- and gamma-opioid receptors in the CNS." @default.
- NCIT_C62054 NCIT_A5 NCIT_C678 @default.
- NCIT_C62054 NCIT_NHC0 "C62054" @default.
- NCIT_C62054 NCIT_P106 "Organic Chemical" @default.
- NCIT_C62054 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C62054 NCIT_P108 "Naloxone" @default.
- NCIT_C62054 NCIT_P207 "C0027358" @default.
- NCIT_C62054 NCIT_P210 "465-65-6" @default.
- NCIT_C62054 NCIT_P319 "36B82AMQ7N" @default.
- NCIT_C62054 NCIT_P322 "FDA" @default.
- NCIT_C62054 NCIT_P325 "A substance that is being studied as a treatment for constipation caused by narcotic medications. It belongs to the family of drugs called narcotic antagonists." @default.
- NCIT_C62054 NCIT_P350 "C19H21NO4" @default.
- NCIT_C62054 NCIT_P366 "Naloxone_Base" @default.
- NCIT_C62054 NCIT_P368 "CHEBI:7459" @default.
- NCIT_C62054 normalizedInformationContent "100" @default.
- NCIT_C62054 referenceCount "1" @default.
- NCIT_C62054 hasExactSynonym "(-)-Naloxone" @default.
- NCIT_C62054 hasExactSynonym "NALOXONE" @default.
- NCIT_C62054 hasExactSynonym "Naloxone" @default.
- NCIT_C62054 hasExactSynonym "naloxone" @default.
- NCIT_C62054 inSubset NCIT_C63923 @default.
- NCIT_C62054 type Class @default.
- NCIT_C62054 isDefinedBy ncit.owl @default.
- NCIT_C62054 label "Naloxone" @default.
- NCIT_C62054 subClassOf NCIT_C1908 @default.
- NCIT_C62054 subClassOf NCIT_C1909 @default.
- NCIT_C62054 subClassOf NCIT_C62054 @default.
- NCIT_C62054 subClassOf NCIT_C681 @default.
- NCIT_C62054 subClassOf NCIT_C78272 @default.