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- NCIT_C62065 IAO_0000115 "A synthetic, dibenzamine alpha adrenergic antagonist with antihypertensive and vasodilatory properties. Phenoxybenzamine non-selectively and irreversibly blocks the postsynaptic alpha-adrenergic receptor in smooth muscle, thereby preventing vasoconstriction, relieving vasospasms, and decreasing peripheral resistance. Reflex tachycardia may occur and may be enhanced by blockade of alpha-2 receptors which enhances norepinephrine release. Phenoxybenzamine is reasonably anticipated to be a human carcinogen." @default.
- NCIT_C62065 NCIT_A5 NCIT_C44435 @default.
- NCIT_C62065 NCIT_NHC0 "C62065" @default.
- NCIT_C62065 NCIT_P106 "Hazardous or Poisonous Substance" @default.
- NCIT_C62065 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C62065 NCIT_P108 "Phenoxybenzamine" @default.
- NCIT_C62065 NCIT_P207 "C0031441" @default.
- NCIT_C62065 NCIT_P210 "59-96-1" @default.
- NCIT_C62065 NCIT_P319 "0TTZ664R7Z" @default.
- NCIT_C62065 NCIT_P322 "FDA" @default.
- NCIT_C62065 NCIT_P350 "C18H22ClNO" @default.
- NCIT_C62065 NCIT_P366 "Phenoxybenzamine_Base" @default.
- NCIT_C62065 normalizedInformationContent "100" @default.
- NCIT_C62065 referenceCount "1" @default.
- NCIT_C62065 hasExactSynonym "N-(2-chloroethyl)-N-(1-methyl-2-phenoxyethyl)-benzenemethanamine" @default.
- NCIT_C62065 hasExactSynonym "PHENOXYBENZAMINE" @default.
- NCIT_C62065 hasExactSynonym "Phenoxybenzamine" @default.
- NCIT_C62065 inSubset NCIT_C63923 @default.
- NCIT_C62065 type Class @default.
- NCIT_C62065 isDefinedBy ncit.owl @default.
- NCIT_C62065 label "Phenoxybenzamine" @default.
- NCIT_C62065 subClassOf NCIT_C1743 @default.
- NCIT_C62065 subClassOf NCIT_C1908 @default.
- NCIT_C62065 subClassOf NCIT_C1909 @default.
- NCIT_C62065 subClassOf NCIT_C1932 @default.
- NCIT_C62065 subClassOf NCIT_C29713 @default.
- NCIT_C62065 subClassOf NCIT_C29747 @default.
- NCIT_C62065 subClassOf NCIT_C347 @default.
- NCIT_C62065 subClassOf NCIT_C45175 @default.
- NCIT_C62065 subClassOf NCIT_C45176 @default.
- NCIT_C62065 subClassOf NCIT_C45178 @default.
- NCIT_C62065 subClassOf NCIT_C62065 @default.
- NCIT_C62065 subClassOf NCIT_C72900 @default.
- NCIT_C62065 subClassOf NCIT_C78272 @default.