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- NCIT_C62076 IAO_0000115 "An agent belonging to the glitazone class of antidiabetic agents with antihyperglycemic and anti-inflammatory activities. In addition to its selective affinity for peroxisome proliferator-activated receptor (PPAR) gamma and its ability to lower blood glucose levels, rosiglitazone also exerts anti-inflammatory activity through its ability to inhibit nuclear factor-kappaB (NF-KB) activity and increase I-kappaB levels. In addition, rosiglitazone may cause fluid retention and may worsen congestive heart failure. This agent is also associated with an increased risk of heart attacks." @default.
- NCIT_C62076 NCIT_A5 NCIT_C2583 @default.
- NCIT_C62076 NCIT_A7 NCIT_C34077 @default.
- NCIT_C62076 NCIT_NHC0 "C62076" @default.
- NCIT_C62076 NCIT_P106 "Organic Chemical" @default.
- NCIT_C62076 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C62076 NCIT_P107 "Rosiglitazone" @default.
- NCIT_C62076 NCIT_P108 "Rosiglitazone" @default.
- NCIT_C62076 NCIT_P207 "C0289313" @default.
- NCIT_C62076 NCIT_P210 "122320-73-4" @default.
- NCIT_C62076 NCIT_P319 "05V02F2KDG" @default.
- NCIT_C62076 NCIT_P322 "CTRP" @default.
- NCIT_C62076 NCIT_P322 "FDA" @default.
- NCIT_C62076 NCIT_P325 "The active ingredient in a drug that helps control the amount of glucose (sugar) in the blood and is being studied in the prevention and treatment of some types of cancer. Rosiglitazone stops cells from growing and may prevent the growth of new blood vessels that tumors need to grow. It is a type of thiazolidinedione and a type of antiangiogenesis agent." @default.
- NCIT_C62076 NCIT_P350 "C18H19N3O3S" @default.
- NCIT_C62076 NCIT_P366 "Rosiglitazone_Base" @default.
- NCIT_C62076 NCIT_P368 "CHEBI:50122" @default.
- NCIT_C62076 normalizedInformationContent "100" @default.
- NCIT_C62076 referenceCount "1" @default.
- NCIT_C62076 hasExactSynonym "ROSIGLITAZONE" @default.
- NCIT_C62076 hasExactSynonym "Rosiglitazone" @default.
- NCIT_C62076 hasExactSynonym "rosiglitazone" @default.
- NCIT_C62076 inSubset NCIT_C116977 @default.
- NCIT_C62076 inSubset NCIT_C116978 @default.
- NCIT_C62076 inSubset NCIT_C63923 @default.
- NCIT_C62076 type Class @default.
- NCIT_C62076 isDefinedBy ncit.owl @default.
- NCIT_C62076 label "Rosiglitazone" @default.
- NCIT_C62076 subClassOf NCIT_C1908 @default.
- NCIT_C62076 subClassOf NCIT_C1909 @default.
- NCIT_C62076 subClassOf NCIT_C1934 @default.
- NCIT_C62076 subClassOf NCIT_C2122 @default.
- NCIT_C62076 subClassOf NCIT_C274 @default.
- NCIT_C62076 subClassOf NCIT_C29711 @default.
- NCIT_C62076 subClassOf NCIT_C62076 @default.
- NCIT_C62076 subClassOf NCIT_C78276 @default.
- NCIT_C62076 subClassOf NCIT_C98241 @default.