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- NCIT_C62496 IAO_0000115 "An orally bioavailable small-molecule receptor tyrosine kinase (RTK) inhibitor with potential antineoplastic activity. Tesevatinib binds to and inhibits several tyrosine receptor kinases that play major roles in tumor cell proliferation and tumor vascularization, including epidermal growth factor receptor (EGFR; ERBB1), epidermal growth factor receptor 2 (HER2; ERBB2), vascular endothelial growth factor receptor (VEGFR), and ephrin B4 (EphB4). This may result in the inhibition of tumor growth and angiogenesis, and tumor regression." @default.
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- NCIT_C62496 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C62496 NCIT_P107 "Tesevatinib" @default.
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- NCIT_C62496 referenceCount "1" @default.
- NCIT_C62496 hasExactSynonym "4-Quinazolinamine, N-(3,4-dichloro-2-fluorophenyl)-6-methoxy-7-(((3aalpha,5beta,6aalpha)-octahydro-2-methylcyclopenta(c)pyrrol-5-yl)methoxy)-" @default.
- NCIT_C62496 hasExactSynonym "EXEL 7647" @default.
- NCIT_C62496 hasExactSynonym "KD 019" @default.
- NCIT_C62496 hasExactSynonym "KD019" @default.
- NCIT_C62496 hasExactSynonym "TESEVATINIB" @default.
- NCIT_C62496 hasExactSynonym "Tesevatinib" @default.
- NCIT_C62496 hasExactSynonym "XL647" @default.
- NCIT_C62496 inSubset NCIT_C116977 @default.
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- NCIT_C62496 type Class @default.
- NCIT_C62496 isDefinedBy ncit.owl @default.
- NCIT_C62496 label "Tesevatinib" @default.
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