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- NCIT_C625 IAO_0000115 "A naturally occurring alcohol found in fruits and vegetables and used as an osmotic diuretic. Mannitol is freely filtered by the glomerulus and poorly reabsorbed from the renal tubule, thereby causing an increase in osmolarity of the glomerular filtrate. An increase in osmolarity limits tubular reabsorption of water and inhibits the renal tubular reabsorption of sodium, chloride, and other solutes, thereby promoting diuresis. In addition, mannitol elevates blood plasma osmolarity, resulting in enhanced flow of water from tissues into interstitial fluid and plasma." @default.
- NCIT_C625 NCIT_NHC0 "C625" @default.
- NCIT_C625 NCIT_P106 "Organic Chemical" @default.
- NCIT_C625 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C625 NCIT_P107 "Mannitol" @default.
- NCIT_C625 NCIT_P108 "Mannitol" @default.
- NCIT_C625 NCIT_P175 "407017" @default.
- NCIT_C625 NCIT_P208 "CL1659099" @default.
- NCIT_C625 NCIT_P210 "69-65-8" @default.
- NCIT_C625 NCIT_P319 "3OWL53L36A" @default.
- NCIT_C625 NCIT_P322 "CTRP" @default.
- NCIT_C625 NCIT_P322 "FDA" @default.
- NCIT_C625 NCIT_P325 "A drug used to decrease swelling of the brain and to treat kidney failure. Mannitol can also be used to open the blood-brain barrier, which allows anticancer medicines to enter the brain and treat brain tumors." @default.
- NCIT_C625 NCIT_P329 "39493" @default.
- NCIT_C625 NCIT_P330 "39493" @default.
- NCIT_C625 NCIT_P350 "C6H14O6" @default.
- NCIT_C625 NCIT_P366 "Mannitol" @default.
- NCIT_C625 NCIT_P368 "CHEBI:16899" @default.
- NCIT_C625 NCIT_P399 "39493" @default.
- NCIT_C625 normalizedInformationContent "100" @default.
- NCIT_C625 referenceCount "1" @default.
- NCIT_C625 hasExactSynonym "D-Mannitol" @default.
- NCIT_C625 hasExactSynonym "MANNITOL" @default.
- NCIT_C625 hasExactSynonym "Mannitol" @default.
- NCIT_C625 hasExactSynonym "Mannitol, D-" @default.
- NCIT_C625 hasExactSynonym "Osmitrol" @default.
- NCIT_C625 hasExactSynonym "Resectisol" @default.
- NCIT_C625 hasExactSynonym "mannitol" @default.
- NCIT_C625 inSubset NCIT_C116977 @default.
- NCIT_C625 inSubset NCIT_C116978 @default.
- NCIT_C625 inSubset NCIT_C176424 @default.
- NCIT_C625 inSubset NCIT_C63923 @default.
- NCIT_C625 type Class @default.
- NCIT_C625 isDefinedBy ncit.owl @default.
- NCIT_C625 label "Mannitol" @default.
- NCIT_C625 subClassOf NCIT_C1908 @default.
- NCIT_C625 subClassOf NCIT_C1909 @default.
- NCIT_C625 subClassOf NCIT_C448 @default.
- NCIT_C625 subClassOf NCIT_C49187 @default.
- NCIT_C625 subClassOf NCIT_C625 @default.
- NCIT_C625 subClassOf NCIT_C78275 @default.