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- NCIT_C62523 IAO_0000115 "A small aminothiazole molecule and cyclin dependent kinase (CDK) inhibitor with potential antineoplastic activity. SNS-032 binds to and prevents the phosphorylation of cyclin-dependent kinases, especially CDK2, 7, and 9 that regulate cell cycle progression. Inhibition of CDKs leads to cell cycle arrest and induces apoptosis. As a result, this agent causes cytotoxicity and prevents further tumor cell growth." @default.
- NCIT_C62523 NCIT_A32 NCIT_C1909 @default.
- NCIT_C62523 NCIT_A7 NCIT_C25842 @default.
- NCIT_C62523 NCIT_NHC0 "C62523" @default.
- NCIT_C62523 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C62523 NCIT_P108 "CDK Inhibitor SNS-032" @default.
- NCIT_C62523 NCIT_P207 "C1451099" @default.
- NCIT_C62523 NCIT_P210 "345627-80-7" @default.
- NCIT_C62523 NCIT_P319 "9979I93686" @default.
- NCIT_C62523 NCIT_P322 "FDA" @default.
- NCIT_C62523 NCIT_P322 "GDC" @default.
- NCIT_C62523 NCIT_P329 "488948" @default.
- NCIT_C62523 NCIT_P330 "488948" @default.
- NCIT_C62523 NCIT_P366 "SNS-032" @default.
- NCIT_C62523 NCIT_P375 "CDK Inhibitor SNS-032" @default.
- NCIT_C62523 NCIT_P399 "488948" @default.
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- NCIT_C62523 NCIT_R146 NCIT_C17761 @default.
- NCIT_C62523 NCIT_R146 NCIT_C17767 @default.
- NCIT_C62523 NCIT_R146 NCIT_C18466 @default.
- NCIT_C62523 NCIT_R146 NCIT_C20027 @default.
- NCIT_C62523 NCIT_R146 NCIT_C26548 @default.
- NCIT_C62523 normalizedInformationContent "100" @default.
- NCIT_C62523 referenceCount "1" @default.
- NCIT_C62523 hasExactSynonym "BMS-387032" @default.
- NCIT_C62523 hasExactSynonym "CDK Inhibitor SNS-032" @default.
- NCIT_C62523 hasExactSynonym "SNS-032" @default.
- NCIT_C62523 inSubset NCIT_C128784 @default.
- NCIT_C62523 inSubset NCIT_C157711 @default.
- NCIT_C62523 inSubset NCIT_C157712 @default.
- NCIT_C62523 inSubset NCIT_C176424 @default.
- NCIT_C62523 inSubset NCIT_C177537 @default.
- NCIT_C62523 inSubset NCIT_C63923 @default.
- NCIT_C62523 type Class @default.
- NCIT_C62523 isDefinedBy ncit.owl @default.
- NCIT_C62523 label "CDK Inhibitor SNS-032" @default.
- NCIT_C62523 subClassOf B2559cc4d9e7c1ab9ad2c28f56cdb5998 @default.
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- NCIT_C62523 subClassOf NCIT_C1404 @default.
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- NCIT_C62523 subClassOf NCIT_C1909 @default.
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- NCIT_C62523 subClassOf NCIT_C274 @default.
- NCIT_C62523 subClassOf NCIT_C471 @default.
- NCIT_C62523 subClassOf NCIT_C61074 @default.
- NCIT_C62523 subClassOf NCIT_C62523 @default.