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- NCIT_C62528 IAO_0000115 "A recombinant, single-chain, anti-CD19/anti-CD3 bispecific monoclonal antibody with potential immunostimulating and antineoplastic activities. Blinatumomab possesses two antigen-recognition sites, one for the CD3 complex, a group of T cell surface glycoproteins that complex with the T cell receptor (TCR), and one for CD19, a tumor-associated antigen (TAA) overexpressed on the surface of B cells. This bispecific monoclonal antibody brings CD19-expressing tumor B-cells and cytotoxic T lymphocytes (CTLs) and helper T lymphocytes (HTLs) together, which may result in the CTL- and HTL-mediated cell death of CD19-expressing B-lymphocytes." @default.
- NCIT_C62528 NCIT_A32 NCIT_C1909 @default.
- NCIT_C62528 NCIT_A7 NCIT_C38894 @default.
- NCIT_C62528 NCIT_NHC0 "C62528" @default.
- NCIT_C62528 NCIT_P106 "Amino Acid, Peptide, or Protein" @default.
- NCIT_C62528 NCIT_P106 "Immunologic Factor" @default.
- NCIT_C62528 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C62528 NCIT_P107 "Blinatumomab" @default.
- NCIT_C62528 NCIT_P108 "Blinatumomab" @default.
- NCIT_C62528 NCIT_P207 "C3853839" @default.
- NCIT_C62528 NCIT_P210 "853426-35-4" @default.
- NCIT_C62528 NCIT_P302 "relapsed or refractory B-cell precursor acute lymphoblastic leukemia (ALL)" @default.
- NCIT_C62528 NCIT_P319 "4FR53SIF3A" @default.
- NCIT_C62528 NCIT_P322 "CTRP" @default.
- NCIT_C62528 NCIT_P322 "FDA" @default.
- NCIT_C62528 NCIT_P322 "GDC" @default.
- NCIT_C62528 NCIT_P329 "487684" @default.
- NCIT_C62528 NCIT_P330 "487684" @default.
- NCIT_C62528 NCIT_P366 "Anti-CD19_Anti-CD3_Bispecific_Monoclonal_Antibody" @default.
- NCIT_C62528 NCIT_P375 "Blinatumomab" @default.
- NCIT_C62528 NCIT_P399 "487684" @default.
- NCIT_C62528 NCIT_R124 NCIT_C17710 @default.
- NCIT_C62528 NCIT_R124 NCIT_C17828 @default.
- NCIT_C62528 NCIT_R124 NCIT_C18219 @default.
- NCIT_C62528 NCIT_R124 NCIT_C19986 @default.
- NCIT_C62528 NCIT_R124 NCIT_C40474 @default.
- NCIT_C62528 NCIT_R125 NCIT_C17828 @default.
- NCIT_C62528 NCIT_R125 NCIT_C17937 @default.
- NCIT_C62528 NCIT_R125 NCIT_C18095 @default.
- NCIT_C62528 NCIT_R125 NCIT_C18839 @default.
- NCIT_C62528 NCIT_R125 NCIT_C21124 @default.
- NCIT_C62528 NCIT_R125 NCIT_C40912 @default.
- NCIT_C62528 normalizedInformationContent "95.413332725061409" @default.
- NCIT_C62528 referenceCount "2" @default.
- NCIT_C62528 hasExactSynonym "AMG 103" @default.
- NCIT_C62528 hasExactSynonym "Anti-CD19 x Anti-CD3 Bispecific Monoclonal Antibody" @default.
- NCIT_C62528 hasExactSynonym "Anti-CD19/Anti-CD3 Recombinant Bispecific Monoclonal Antibody MT103" @default.
- NCIT_C62528 hasExactSynonym "BLINATUMOMAB" @default.
- NCIT_C62528 hasExactSynonym "Blinatumomab" @default.
- NCIT_C62528 hasExactSynonym "Blincyto" @default.
- NCIT_C62528 hasExactSynonym "MEDI-538" @default.
- NCIT_C62528 hasExactSynonym "MEDI538" @default.
- NCIT_C62528 hasExactSynonym "MT-103" @default.
- NCIT_C62528 hasExactSynonym "MT103" @default.
- NCIT_C62528 inSubset NCIT_C116977 @default.
- NCIT_C62528 inSubset NCIT_C116978 @default.
- NCIT_C62528 inSubset NCIT_C128784 @default.
- NCIT_C62528 inSubset NCIT_C157711 @default.
- NCIT_C62528 inSubset NCIT_C157712 @default.
- NCIT_C62528 inSubset NCIT_C176424 @default.
- NCIT_C62528 inSubset NCIT_C177537 @default.
- NCIT_C62528 inSubset NCIT_C63923 @default.
- NCIT_C62528 type Class @default.
- NCIT_C62528 isDefinedBy ncit.owl @default.
- NCIT_C62528 label "Blinatumomab" @default.
- NCIT_C62528 subClassOf B2cd3e3552db1d8d3ebf6577f927a750f @default.
- NCIT_C62528 subClassOf Be65b703e9d92ca9f4d36b86e5e1e69ae @default.
- NCIT_C62528 subClassOf Bf41f97125668d7ccbc3fdcf109642aba @default.
- NCIT_C62528 subClassOf Bf534817176b49f5d567f2ed4c9a083ba @default.
- NCIT_C62528 subClassOf NCIT_C112883 @default.
- NCIT_C62528 subClassOf NCIT_C112889 @default.
- NCIT_C62528 subClassOf NCIT_C129820 @default.
- NCIT_C62528 subClassOf NCIT_C129821 @default.
- NCIT_C62528 subClassOf NCIT_C129822 @default.
- NCIT_C62528 subClassOf NCIT_C1454 @default.
- NCIT_C62528 subClassOf NCIT_C163758 @default.
- NCIT_C62528 subClassOf NCIT_C1908 @default.
- NCIT_C62528 subClassOf NCIT_C1909 @default.
- NCIT_C62528 subClassOf NCIT_C198634 @default.
- NCIT_C62528 subClassOf NCIT_C201282 @default.
- NCIT_C62528 subClassOf NCIT_C20401 @default.
- NCIT_C62528 subClassOf NCIT_C274 @default.
- NCIT_C62528 subClassOf NCIT_C28227 @default.
- NCIT_C62528 subClassOf NCIT_C307 @default.
- NCIT_C62528 subClassOf NCIT_C308 @default.
- NCIT_C62528 subClassOf NCIT_C62528 @default.