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- NCIT_C638 IAO_0000115 "The hydrochloride salt of methadone, a synthetic opioid with analgesic activity. Similar to morphine and other morphine-like agents, methadone mimics the actions of endogenous peptides at CNS opioid receptors, primarily the mu-receptor, resulting in characteristic morphine-like effects including analgesia, euphoria, sedation, respiratory depression, miosis, bradycardia and physical dependence. Because of the prolonged half-life of methadone compared to other morphine-like agents such as heroin, the onset of opiate withdrawal symptoms is slower, the duration of opiate withdrawal is prolonged, and opiate withdrawal symptoms are less severe." @default.
- NCIT_C638 NCIT_A6 NCIT_C62044 @default.
- NCIT_C638 NCIT_A7 NCIT_C118985 @default.
- NCIT_C638 NCIT_NHC0 "C638" @default.
- NCIT_C638 NCIT_P106 "Organic Chemical" @default.
- NCIT_C638 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C638 NCIT_P107 "Methadone Hydrochloride" @default.
- NCIT_C638 NCIT_P108 "Methadone Hydrochloride" @default.
- NCIT_C638 NCIT_P175 "19600" @default.
- NCIT_C638 NCIT_P207 "C0721688" @default.
- NCIT_C638 NCIT_P210 "1095-90-5" @default.
- NCIT_C638 NCIT_P319 "229809935B" @default.
- NCIT_C638 NCIT_P322 "CTRP" @default.
- NCIT_C638 NCIT_P322 "FDA" @default.
- NCIT_C638 NCIT_P325 "A drug used to treat moderate to severe pain that does not respond to other types of pain medicine. It is also used to help people who are addicted to opioid drugs such as heroin. Methadone hydrochloride binds to opioid receptors in the central nervous system. It is a type of analgesic agent and a type of opioid." @default.
- NCIT_C638 NCIT_P329 "39498" @default.
- NCIT_C638 NCIT_P330 "39498" @default.
- NCIT_C638 NCIT_P350 "C21H27NO.HCl" @default.
- NCIT_C638 NCIT_P366 "Methadone" @default.
- NCIT_C638 NCIT_P368 "CHEBI:50140" @default.
- NCIT_C638 NCIT_P399 "39498" @default.
- NCIT_C638 NCIT_R122 NCIT_C16484 @default.
- NCIT_C638 NCIT_R122 NCIT_C16486 @default.
- NCIT_C638 NCIT_R122 NCIT_C16554 @default.
- NCIT_C638 NCIT_R122 NCIT_C16865 @default.
- NCIT_C638 NCIT_R122 NCIT_C16946 @default.
- NCIT_C638 NCIT_R122 NCIT_C17021 @default.
- NCIT_C638 NCIT_R122 NCIT_C17573 @default.
- NCIT_C638 NCIT_R122 NCIT_C20027 @default.
- NCIT_C638 NCIT_R122 NCIT_C26548 @default.
- NCIT_C638 NCIT_R122 NCIT_C28459 @default.
- NCIT_C638 NCIT_R122 NCIT_C40050 @default.
- NCIT_C638 NCIT_R122 NCIT_C45999 @default.
- NCIT_C638 NCIT_R122 NCIT_C46000 @default.
- NCIT_C638 normalizedInformationContent "100" @default.
- NCIT_C638 referenceCount "1" @default.
- NCIT_C638 hasExactSynonym "Adanon" @default.
- NCIT_C638 hasExactSynonym "Althose" @default.
- NCIT_C638 hasExactSynonym "Dolophine" @default.
- NCIT_C638 hasExactSynonym "METHADONE HYDROCHLORIDE" @default.
- NCIT_C638 hasExactSynonym "Methadone Hydrochloride" @default.
- NCIT_C638 hasExactSynonym "Methadose" @default.
- NCIT_C638 hasExactSynonym "methadone hydrochloride" @default.
- NCIT_C638 inSubset NCIT_C116977 @default.
- NCIT_C638 inSubset NCIT_C116978 @default.
- NCIT_C638 inSubset NCIT_C176424 @default.
- NCIT_C638 inSubset NCIT_C63923 @default.
- NCIT_C638 type Class @default.
- NCIT_C638 isDefinedBy ncit.owl @default.
- NCIT_C638 label "Methadone Hydrochloride" @default.
- NCIT_C638 subClassOf B01b618660be6dd5cebc843c691caaefe @default.
- NCIT_C638 subClassOf B1c4dcc9b5e239f6b572ce6c1ac0096f1 @default.
- NCIT_C638 subClassOf B2ca2c2229eae998517f1593ff9719c77 @default.
- NCIT_C638 subClassOf B715ab6cc7e405cc0546824838c2b5e0d @default.
- NCIT_C638 subClassOf Baefa3380253e868006e70c1b90db8229 @default.
- NCIT_C638 subClassOf Bcf24e832e73076f6b97fd5e2082e16d4 @default.
- NCIT_C638 subClassOf Bdf60265c9270cb527136816c985e2094 @default.
- NCIT_C638 subClassOf Bebcc6d204bb5de5566ae911b29f3dbd8 @default.
- NCIT_C638 subClassOf NCIT_C1506 @default.
- NCIT_C638 subClassOf NCIT_C1908 @default.
- NCIT_C638 subClassOf NCIT_C1909 @default.
- NCIT_C638 subClassOf NCIT_C1913 @default.
- NCIT_C638 subClassOf NCIT_C1916 @default.
- NCIT_C638 subClassOf NCIT_C221 @default.
- NCIT_C638 subClassOf NCIT_C638 @default.
- NCIT_C638 subClassOf NCIT_C67413 @default.
- NCIT_C638 subClassOf NCIT_C718 @default.
- NCIT_C638 subClassOf NCIT_C78272 @default.