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- NCIT_C64338 IAO_0000115 "An oral formulation of the phosphate salt of fludarabine, a synthetic purine nucleoside analogue antimetabolite with antineoplastic activity. Fudarabine is preferentially transported into malignant cells and metabolized by deoxycytidine kinase to its active form, 2-fluoro-ara-ATP; 2-fluoro-ara-ATP competes directly with deoxyadenosine triphosphate (dATP) and inhibits alpha DNA polymerase, RNA reductase, and DNA primase, which may result in inhibition of DNA synthesis and cell death." @default.
- NCIT_C64338 NCIT_A32 NCIT_C1909 @default.
- NCIT_C64338 NCIT_NHC0 "C64338" @default.
- NCIT_C64338 NCIT_P106 "Nucleic Acid, Nucleoside, or Nucleotide" @default.
- NCIT_C64338 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C64338 NCIT_P108 "Oral Fludarabine Phosphate" @default.
- NCIT_C64338 NCIT_P207 "C1831839" @default.
- NCIT_C64338 NCIT_P322 "GDC" @default.
- NCIT_C64338 NCIT_P329 "486428" @default.
- NCIT_C64338 NCIT_P330 "486428" @default.
- NCIT_C64338 NCIT_P366 "Oral_Fludarabine_Phosphate" @default.
- NCIT_C64338 NCIT_P375 "Oral Fludarabine Phosphate" @default.
- NCIT_C64338 NCIT_P399 "486428" @default.
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- NCIT_C64338 normalizedInformationContent "100" @default.
- NCIT_C64338 referenceCount "1" @default.
- NCIT_C64338 hasExactSynonym "Fludara Oral" @default.
- NCIT_C64338 hasExactSynonym "Oral Fludarabine Phosphate" @default.
- NCIT_C64338 inSubset NCIT_C128784 @default.
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- NCIT_C64338 type Class @default.
- NCIT_C64338 isDefinedBy ncit.owl @default.
- NCIT_C64338 label "Oral Fludarabine Phosphate" @default.
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- NCIT_C64338 subClassOf NCIT_C272 @default.
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