Matches in Ubergraph for { <http://purl.obolibrary.org/obo/NCIT_C64634> ?p ?o ?g. }
Showing items 1 to 73 of
73
with 100 items per page.
- NCIT_C64634 IAO_0000115 "A naturally-occurring salinosporamide, isolated from the marine actinomycete Salinospora tropica, with potential antineoplastic activity. Marizomib irreversibly binds to and inhibits the 20S catalytic core subunit of the proteasome by covalently modifying its active site threonine residues; inhibition of ubiquitin-proteasome mediated proteolysis results in an accumulation of poly-ubiquitinated proteins, which may result in the disruption of cellular processes, cell cycle arrest, the induction of apoptosis, and the inhibition of tumor growth and angiogenesis. This agent more may more potent and selective than the proteasome inhibitor bortezomib." @default.
- NCIT_C64634 NCIT_A32 NCIT_C1909 @default.
- NCIT_C64634 NCIT_A7 NCIT_C13737 @default.
- NCIT_C64634 NCIT_NHC0 "C64634" @default.
- NCIT_C64634 NCIT_P106 "Organic Chemical" @default.
- NCIT_C64634 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C64634 NCIT_P107 "Marizomib" @default.
- NCIT_C64634 NCIT_P108 "Marizomib" @default.
- NCIT_C64634 NCIT_P207 "C1259854" @default.
- NCIT_C64634 NCIT_P210 "437742-34-2" @default.
- NCIT_C64634 NCIT_P319 "703P9YDP7F" @default.
- NCIT_C64634 NCIT_P322 "CTRP" @default.
- NCIT_C64634 NCIT_P322 "FDA" @default.
- NCIT_C64634 NCIT_P322 "GDC" @default.
- NCIT_C64634 NCIT_P329 "518316" @default.
- NCIT_C64634 NCIT_P330 "518316" @default.
- NCIT_C64634 NCIT_P350 "C15H20ClNO4" @default.
- NCIT_C64634 NCIT_P366 "NPI-0052" @default.
- NCIT_C64634 NCIT_P368 "CHEBI:48045" @default.
- NCIT_C64634 NCIT_P375 "Marizomib" @default.
- NCIT_C64634 NCIT_P399 "518316" @default.
- NCIT_C64634 NCIT_R124 NCIT_C17710 @default.
- NCIT_C64634 NCIT_R124 NCIT_C17828 @default.
- NCIT_C64634 NCIT_R124 NCIT_C18104 @default.
- NCIT_C64634 NCIT_R124 NCIT_C19406 @default.
- NCIT_C64634 NCIT_R124 NCIT_C19536 @default.
- NCIT_C64634 NCIT_R124 NCIT_C19903 @default.
- NCIT_C64634 NCIT_R124 NCIT_C19986 @default.
- NCIT_C64634 NCIT_R124 NCIT_C21198 @default.
- NCIT_C64634 NCIT_R124 NCIT_C28498 @default.
- NCIT_C64634 NCIT_R124 NCIT_C41597 @default.
- NCIT_C64634 NCIT_R124 NCIT_C61559 @default.
- NCIT_C64634 NCIT_R125 NCIT_C17133 @default.
- NCIT_C64634 NCIT_R125 NCIT_C17828 @default.
- NCIT_C64634 NCIT_R125 NCIT_C20150 @default.
- NCIT_C64634 NCIT_R125 NCIT_C20480 @default.
- NCIT_C64634 NCIT_R125 NCIT_C40715 @default.
- NCIT_C64634 NCIT_R125 NCIT_C40821 @default.
- NCIT_C64634 NCIT_R125 NCIT_C41515 @default.
- NCIT_C64634 NCIT_R125 NCIT_C51037 @default.
- NCIT_C64634 normalizedInformationContent "100" @default.
- NCIT_C64634 referenceCount "1" @default.
- NCIT_C64634 hasExactSynonym "(1R,4R,5S)-4-(2-chloroethyl)-1-{(S)-[(1S)-cyclohex-2-en-1-yl]hydroxymethyl}-5-methyl-6-oxa-2-azabicyclo[3.2.0]heptane-3,7-dione" @default.
- NCIT_C64634 hasExactSynonym "MARIZOMIB" @default.
- NCIT_C64634 hasExactSynonym "ML 858" @default.
- NCIT_C64634 hasExactSynonym "Marizomib" @default.
- NCIT_C64634 hasExactSynonym "NPI-0052" @default.
- NCIT_C64634 hasExactSynonym "Salinosporamide A" @default.
- NCIT_C64634 hasExactSynonym "Salinosporin A" @default.
- NCIT_C64634 inSubset NCIT_C116977 @default.
- NCIT_C64634 inSubset NCIT_C116978 @default.
- NCIT_C64634 inSubset NCIT_C128784 @default.
- NCIT_C64634 inSubset NCIT_C157711 @default.
- NCIT_C64634 inSubset NCIT_C157712 @default.
- NCIT_C64634 inSubset NCIT_C176424 @default.
- NCIT_C64634 inSubset NCIT_C177537 @default.
- NCIT_C64634 inSubset NCIT_C63923 @default.
- NCIT_C64634 type Class @default.
- NCIT_C64634 isDefinedBy ncit.owl @default.
- NCIT_C64634 label "Marizomib" @default.
- NCIT_C64634 subClassOf B0b0d31242bb7f622622318797f8d0d5c @default.
- NCIT_C64634 subClassOf B5648b997f71d3aa1a6d5a08c62e5e671 @default.
- NCIT_C64634 subClassOf B7570e991cda0ac6e4136ad9634aca779 @default.
- NCIT_C64634 subClassOf B962ea1aa45ddbc29585a9f95dd2a05c5 @default.
- NCIT_C64634 subClassOf Ba56940d82956cd534e8d706a72dfe09f @default.
- NCIT_C64634 subClassOf Bb84f52348bb19beb207f3abd48ca3659 @default.
- NCIT_C64634 subClassOf NCIT_C163758 @default.
- NCIT_C64634 subClassOf NCIT_C1908 @default.
- NCIT_C64634 subClassOf NCIT_C1909 @default.
- NCIT_C64634 subClassOf NCIT_C2160 @default.
- NCIT_C64634 subClassOf NCIT_C274 @default.
- NCIT_C64634 subClassOf NCIT_C471 @default.
- NCIT_C64634 subClassOf NCIT_C64634 @default.