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- NCIT_C64764 IAO_0000115 "The dihydrochloride salt of efatutazone, an orally bioavailable agonist of peroxisome proliferator-activated receptor gamma (PPAR-gamma) with potential antineoplastic activity. Efatutazone binds to and activates PPAR-gamma, a nuclear hormone receptor and a ligand-activated transcription factor controling gene expression involved in macromolecule metabolism and cell differentiation, specifically adipocyte differentiation. Mediated through activation of PPAR-gamma, this agent is capable of inducing cell differentiation and apoptosis, thereby leading to a reduction in cellular proliferation." @default.
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- NCIT_C64764 NCIT_A7 NCIT_C34077 @default.
- NCIT_C64764 NCIT_NHC0 "C64764" @default.
- NCIT_C64764 NCIT_P106 "Organic Chemical" @default.
- NCIT_C64764 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C64764 NCIT_P107 "Efatutazone Dihydrochloride" @default.
- NCIT_C64764 NCIT_P108 "Efatutazone Dihydrochloride" @default.
- NCIT_C64764 NCIT_P207 "C1721778" @default.
- NCIT_C64764 NCIT_P210 "223132-38-5" @default.
- NCIT_C64764 NCIT_P319 "76B44WEA8O" @default.
- NCIT_C64764 NCIT_P322 "CTRP" @default.
- NCIT_C64764 NCIT_P322 "FDA" @default.
- NCIT_C64764 NCIT_P322 "GDC" @default.
- NCIT_C64764 NCIT_P329 "529846" @default.
- NCIT_C64764 NCIT_P330 "529846" @default.
- NCIT_C64764 NCIT_P350 "C27H26N4O4S.2ClH" @default.
- NCIT_C64764 NCIT_P366 "CS-7017" @default.
- NCIT_C64764 NCIT_P375 "Efatutazone Dihydrochloride" @default.
- NCIT_C64764 NCIT_P399 "529846" @default.
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- NCIT_C64764 NCIT_R146 NCIT_C17207 @default.
- NCIT_C64764 NCIT_R146 NCIT_C17671 @default.
- NCIT_C64764 NCIT_R146 NCIT_C17728 @default.
- NCIT_C64764 NCIT_R146 NCIT_C18106 @default.
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- NCIT_C64764 NCIT_R146 NCIT_C20027 @default.
- NCIT_C64764 NCIT_R146 NCIT_C26199 @default.
- NCIT_C64764 NCIT_R146 NCIT_C26548 @default.
- NCIT_C64764 NCIT_R146 NCIT_C34077 @default.
- NCIT_C64764 normalizedInformationContent "100" @default.
- NCIT_C64764 referenceCount "1" @default.
- NCIT_C64764 hasExactSynonym "2,4-thiazolidinedione, 5-((4-((6-(4-amino-3,5-dimethylphenoxy)-1-methyl-1h-benzimidazol-2-yl)methoxy)phenyl)methyl)-, Hydrochloride (1:2)" @default.
- NCIT_C64764 hasExactSynonym "CS-7017" @default.
- NCIT_C64764 hasExactSynonym "EFATUTAZONE DIHYDROCHLORIDE" @default.
- NCIT_C64764 hasExactSynonym "Efatutazone Dihydrochloride" @default.
- NCIT_C64764 hasExactSynonym "Inolitazone Dihydrochloride" @default.
- NCIT_C64764 inSubset NCIT_C116977 @default.
- NCIT_C64764 inSubset NCIT_C116978 @default.
- NCIT_C64764 inSubset NCIT_C128784 @default.
- NCIT_C64764 inSubset NCIT_C157711 @default.
- NCIT_C64764 inSubset NCIT_C157712 @default.
- NCIT_C64764 inSubset NCIT_C176424 @default.
- NCIT_C64764 inSubset NCIT_C177537 @default.
- NCIT_C64764 inSubset NCIT_C63923 @default.
- NCIT_C64764 type Class @default.
- NCIT_C64764 isDefinedBy ncit.owl @default.
- NCIT_C64764 label "Efatutazone Dihydrochloride" @default.
- NCIT_C64764 subClassOf B86fda216d1cf1190cb4d0fc2f483c0ae @default.
- NCIT_C64764 subClassOf B9aee9edcbf1176ecde72e202106b6ac4 @default.
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- NCIT_C64764 subClassOf NCIT_C1908 @default.
- NCIT_C64764 subClassOf NCIT_C1909 @default.
- NCIT_C64764 subClassOf NCIT_C1934 @default.
- NCIT_C64764 subClassOf NCIT_C2122 @default.
- NCIT_C64764 subClassOf NCIT_C274 @default.
- NCIT_C64764 subClassOf NCIT_C64764 @default.