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- NCIT_C65111 IAO_0000115 "A long-acting aqueous gel preparation of lanreotide, a synthetic cyclic octapeptide analogue of somatostatin. Lanreotide inhibits the secretion of growth hormone (GH) by binding to pituitary somatostatin receptors, and may inhibit the release of various other hormones, including thyroid stimulating hormone (TSH) and the gastroenteropancreatic hormones insulin, glucagon and gastrin. This agent also decreases circulating total and free insulin-like growth factor 1 (IGF-I). Lanreotide exhibits a high binding affinity for somatostatin receptor 2 (SSTR-2) and a lesser binding affinity for SSTR-5. However, compared to octreotide, this agent is less potent in inhibiting the release of growth hormone from the pituitary gland." @default.
- NCIT_C65111 NCIT_A7 NCIT_C17922 @default.
- NCIT_C65111 NCIT_A7 NCIT_C17927 @default.
- NCIT_C65111 NCIT_NHC0 "C65111" @default.
- NCIT_C65111 NCIT_P106 "Amino Acid, Peptide, or Protein" @default.
- NCIT_C65111 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C65111 NCIT_P107 "Lanreotide Long-Acting Aqueous Gel" @default.
- NCIT_C65111 NCIT_P108 "Lanreotide Long-Acting Aqueous Gel" @default.
- NCIT_C65111 NCIT_P207 "C1831852" @default.
- NCIT_C65111 NCIT_P322 "CTRP" @default.
- NCIT_C65111 NCIT_P329 "486962" @default.
- NCIT_C65111 NCIT_P330 "486962" @default.
- NCIT_C65111 NCIT_P366 "Lanreotide_Long-Acting_Aqueous_Gel" @default.
- NCIT_C65111 NCIT_P399 "486962" @default.
- NCIT_C65111 normalizedInformationContent "100" @default.
- NCIT_C65111 referenceCount "1" @default.
- NCIT_C65111 hasExactSynonym "Lanreotide Autogel" @default.
- NCIT_C65111 hasExactSynonym "Lanreotide Long-Acting Aqueous Gel" @default.
- NCIT_C65111 hasExactSynonym "Somatuline Autogel" @default.
- NCIT_C65111 hasExactSynonym "lanreotide (long-acting aqueous preparation)" @default.
- NCIT_C65111 inSubset NCIT_C116977 @default.
- NCIT_C65111 inSubset NCIT_C116978 @default.
- NCIT_C65111 inSubset NCIT_C176424 @default.
- NCIT_C65111 type Class @default.
- NCIT_C65111 isDefinedBy ncit.owl @default.
- NCIT_C65111 label "Lanreotide Long-Acting Aqueous Gel" @default.
- NCIT_C65111 subClassOf NCIT_C147908 @default.
- NCIT_C65111 subClassOf NCIT_C1908 @default.
- NCIT_C65111 subClassOf NCIT_C1909 @default.
- NCIT_C65111 subClassOf NCIT_C548 @default.
- NCIT_C65111 subClassOf NCIT_C62799 @default.
- NCIT_C65111 subClassOf NCIT_C65111 @default.