Matches in Ubergraph for { <http://purl.obolibrary.org/obo/NCIT_C652> ?p ?o ?g. }
Showing items 1 to 46 of
46
with 100 items per page.
- NCIT_C652 IAO_0000115 "The hydrochloride salt form of mexiletine, a local anesthetic and antiarrhythmic (Class IB) agent structurally related to lidocaine. Mexiletine exerts its antiarrhythmic effect by inhibiting the inward sodium current in cardiac cells, thereby reducing the rate of rise of the cardiac action potential (phase 0) and decreases automaticity in the Purkinje fibers. This slows nerve impulses in the heart and stabilizes the heartbeat. Mexiletine's anesthetic activity is due to its ability to block sodium influx in peripheral nerves, thereby reducing the rate and intensity of pain impulses reaching the central nervous system." @default.
- NCIT_C652 NCIT_A6 NCIT_C62047 @default.
- NCIT_C652 NCIT_NHC0 "C652" @default.
- NCIT_C652 NCIT_P106 "Organic Chemical" @default.
- NCIT_C652 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C652 NCIT_P108 "Mexiletine Hydrochloride" @default.
- NCIT_C652 NCIT_P207 "C0543459" @default.
- NCIT_C652 NCIT_P210 "5370-01-4" @default.
- NCIT_C652 NCIT_P319 "606D60IS38" @default.
- NCIT_C652 NCIT_P322 "FDA" @default.
- NCIT_C652 NCIT_P350 "C11H17NO.HCl" @default.
- NCIT_C652 NCIT_P366 "Mexiletine" @default.
- NCIT_C652 NCIT_P368 "CHEBI:6917" @default.
- NCIT_C652 NCIT_R122 NCIT_C16484 @default.
- NCIT_C652 NCIT_R122 NCIT_C16486 @default.
- NCIT_C652 NCIT_R122 NCIT_C16554 @default.
- NCIT_C652 NCIT_R122 NCIT_C16865 @default.
- NCIT_C652 NCIT_R122 NCIT_C16946 @default.
- NCIT_C652 NCIT_R122 NCIT_C17021 @default.
- NCIT_C652 NCIT_R122 NCIT_C17287 @default.
- NCIT_C652 NCIT_R122 NCIT_C17673 @default.
- NCIT_C652 NCIT_R122 NCIT_C20027 @default.
- NCIT_C652 NCIT_R122 NCIT_C26548 @default.
- NCIT_C652 NCIT_R122 NCIT_C28459 @default.
- NCIT_C652 normalizedInformationContent "100" @default.
- NCIT_C652 referenceCount "1" @default.
- NCIT_C652 hasExactSynonym "1-(2,6-Dimethylphenoxy)-2-propanamine Hydrochloride" @default.
- NCIT_C652 hasExactSynonym "1-Methyl-2-(2,6-xylyloxy)ethylamine Hydrochloride" @default.
- NCIT_C652 hasExactSynonym "Ko 1173 Cl" @default.
- NCIT_C652 hasExactSynonym "MEXILETINE HYDROCHLORIDE" @default.
- NCIT_C652 hasExactSynonym "Mexiletine Hydrochloride" @default.
- NCIT_C652 hasExactSynonym "Mexitil" @default.
- NCIT_C652 inSubset NCIT_C63923 @default.
- NCIT_C652 type Class @default.
- NCIT_C652 isDefinedBy ncit.owl @default.
- NCIT_C652 label "Mexiletine Hydrochloride" @default.
- NCIT_C652 subClassOf B72cd334f89a497e17e4aa0feff884984 @default.
- NCIT_C652 subClassOf B880ac303a99d500a08f175f9986dc6b7 @default.
- NCIT_C652 subClassOf Bc39f920366bf23d7ebe1c8e7da63c3e6 @default.
- NCIT_C652 subClassOf Bd877622cd7d47350c117fca080b95367 @default.
- NCIT_C652 subClassOf NCIT_C1908 @default.
- NCIT_C652 subClassOf NCIT_C1909 @default.
- NCIT_C652 subClassOf NCIT_C47793 @default.
- NCIT_C652 subClassOf NCIT_C652 @default.
- NCIT_C652 subClassOf NCIT_C78274 @default.
- NCIT_C652 subClassOf NCIT_C93038 @default.