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- NCIT_C65230 IAO_0000115 "The maleate salt of amlodipine, a synthetic phenylpyridine vasodilator with antihypertensive and antianginal effects. Amlodipine inhibits the influx of extracellular calcium ions into myocardial and peripheral vascular smooth muscle cells, thereby preventing vascular and myocardial contraction. Furthermore, decreased myocardial contractility and dilation of the main coronary and systemic arteries lead to increased blood flow and oxygen delivery to the myocardial tissue and decreases total peripheral resistance. This agent may also modulate multi-drug resistance (MDR) activity through inhibition of the p-glycoprotein efflux pump." @default.
- NCIT_C65230 NCIT_A6 NCIT_C61635 @default.
- NCIT_C65230 NCIT_NHC0 "C65230" @default.
- NCIT_C65230 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C65230 NCIT_P108 "Amlodipine Maleate" @default.
- NCIT_C65230 NCIT_P207 "C0886700" @default.
- NCIT_C65230 NCIT_P210 "88150-47-4" @default.
- NCIT_C65230 NCIT_P319 "CQ27G2BZJM" @default.
- NCIT_C65230 NCIT_P322 "FDA" @default.
- NCIT_C65230 NCIT_P350 "C20H25ClN2O5.C4H4O4" @default.
- NCIT_C65230 NCIT_P366 "Amlodipine_Maleate" @default.
- NCIT_C65230 normalizedInformationContent "100" @default.
- NCIT_C65230 referenceCount "1" @default.
- NCIT_C65230 hasExactSynonym "AMLODIPINE MALEATE" @default.
- NCIT_C65230 hasExactSynonym "Amlodipine Maleate" @default.
- NCIT_C65230 inSubset NCIT_C63923 @default.
- NCIT_C65230 type Class @default.
- NCIT_C65230 isDefinedBy ncit.owl @default.
- NCIT_C65230 label "Amlodipine Maleate" @default.
- NCIT_C65230 subClassOf NCIT_C1908 @default.
- NCIT_C65230 subClassOf NCIT_C1909 @default.
- NCIT_C65230 subClassOf NCIT_C270 @default.
- NCIT_C65230 subClassOf NCIT_C333 @default.
- NCIT_C65230 subClassOf NCIT_C65230 @default.
- NCIT_C65230 subClassOf NCIT_C78274 @default.
- NCIT_C65230 subClassOf NCIT_C93038 @default.