Matches in Ubergraph for { <http://purl.obolibrary.org/obo/NCIT_C65246> ?p ?o ?g. }
Showing items 1 to 27 of
27
with 100 items per page.
- NCIT_C65246 IAO_0000115 "The hydrochloride salt of bacampicillin, a prodrug of ampicillin, a broad-spectrum, semisynthetic, beta-lactam aminopenicillin antibiotic with bactericidal activity. Bacampicillin is hydrolyzed in vivo by esterases to its active metabolite ampicillin. Ampicillin binds to and inactivates penicillin-binding proteins (PBP) located on the inner membrane of the bacterial cell wall. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This interrupts bacterial cell wall synthesis and results in the weakening of the bacterial cell wall and causes cell lysis." @default.
- NCIT_C65246 NCIT_A6 NCIT_C65245 @default.
- NCIT_C65246 NCIT_NHC0 "C65246" @default.
- NCIT_C65246 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C65246 NCIT_P108 "Bacampicillin Hydrochloride" @default.
- NCIT_C65246 NCIT_P207 "C1122338" @default.
- NCIT_C65246 NCIT_P210 "37661-08-8" @default.
- NCIT_C65246 NCIT_P319 "PM034U953T" @default.
- NCIT_C65246 NCIT_P322 "FDA" @default.
- NCIT_C65246 NCIT_P350 "C21H27N3O7S.ClH" @default.
- NCIT_C65246 NCIT_P366 "Bacampicillin_Hydrochloride" @default.
- NCIT_C65246 NCIT_P368 "CHEBI:2969" @default.
- NCIT_C65246 normalizedInformationContent "100" @default.
- NCIT_C65246 referenceCount "1" @default.
- NCIT_C65246 hasExactSynonym "BACAMPICILLIN HYDROCHLORIDE" @default.
- NCIT_C65246 hasExactSynonym "Bacampicillin Hydrochloride" @default.
- NCIT_C65246 inSubset NCIT_C63923 @default.
- NCIT_C65246 type Class @default.
- NCIT_C65246 isDefinedBy ncit.owl @default.
- NCIT_C65246 label "Bacampicillin Hydrochloride" @default.
- NCIT_C65246 subClassOf NCIT_C1500 @default.
- NCIT_C65246 subClassOf NCIT_C1908 @default.
- NCIT_C65246 subClassOf NCIT_C1909 @default.
- NCIT_C65246 subClassOf NCIT_C254 @default.
- NCIT_C65246 subClassOf NCIT_C258 @default.
- NCIT_C65246 subClassOf NCIT_C260 @default.
- NCIT_C65246 subClassOf NCIT_C65246 @default.