Matches in Ubergraph for { <http://purl.obolibrary.org/obo/NCIT_C65268> ?p ?o ?g. }
Showing items 1 to 32 of
32
with 100 items per page.
- NCIT_C65268 IAO_0000115 "The mesylate salt of bitolterol, a diester sympathomimetic amine with bronchodilator activity. As an ester prodrug, bitolterol is hydrolyzed by esterases to its active metabolite colterol (N-t-butylarterenol). Colterol selectively binds to and activates beta-2 adrenergic receptors in bronchiolar smooth muscle, thereby causing stimulation of adenyl cyclase, the enzyme that catalyzes the conversion of adenosine triphosphate (ATP) to cyclic-3',5'-adenosine monophosphate (cAMP). Increased intracellular cAMP levels cause relaxation of bronchial smooth muscle. This increases air flow and prevents bronchospasms and may eventually lead to an improvement of airway function." @default.
- NCIT_C65268 NCIT_A6 NCIT_C65267 @default.
- NCIT_C65268 NCIT_NHC0 "C65268" @default.
- NCIT_C65268 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C65268 NCIT_P108 "Bitolterol Mesylate" @default.
- NCIT_C65268 NCIT_P207 "C0106575" @default.
- NCIT_C65268 NCIT_P210 "30392-41-7" @default.
- NCIT_C65268 NCIT_P319 "4E53T3611U" @default.
- NCIT_C65268 NCIT_P322 "FDA" @default.
- NCIT_C65268 NCIT_P350 "C28H31NO5.CH4O3S" @default.
- NCIT_C65268 NCIT_P366 "Bitolterol_Mesylate" @default.
- NCIT_C65268 NCIT_P368 "CHEBI:3134" @default.
- NCIT_C65268 normalizedInformationContent "100" @default.
- NCIT_C65268 referenceCount "1" @default.
- NCIT_C65268 hasExactSynonym "Alpha-[tert-butylaminomethyl]-3,4- dihydroxybenzyl alcohol 3,4-di(p-toluate) Methanesulfonate" @default.
- NCIT_C65268 hasExactSynonym "BITOLTEROL MESYLATE" @default.
- NCIT_C65268 hasExactSynonym "Bitolterol Mesylate" @default.
- NCIT_C65268 hasExactSynonym "WIN 37284" @default.
- NCIT_C65268 inSubset NCIT_C63923 @default.
- NCIT_C65268 type Class @default.
- NCIT_C65268 isDefinedBy ncit.owl @default.
- NCIT_C65268 label "Bitolterol Mesylate" @default.
- NCIT_C65268 subClassOf NCIT_C1908 @default.
- NCIT_C65268 subClassOf NCIT_C1909 @default.
- NCIT_C65268 subClassOf NCIT_C29712 @default.
- NCIT_C65268 subClassOf NCIT_C29747 @default.
- NCIT_C65268 subClassOf NCIT_C319 @default.
- NCIT_C65268 subClassOf NCIT_C48149 @default.
- NCIT_C65268 subClassOf NCIT_C65268 @default.
- NCIT_C65268 subClassOf NCIT_C78272 @default.
- NCIT_C65268 subClassOf NCIT_C78273 @default.
- NCIT_C65268 subClassOf NCIT_C87053 @default.