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- NCIT_C65318 IAO_0000115 "The hydrochloride salt of chloroquine, a synthetic quinoline with antimalarial and anti-inflammatory properties. Chloroquine is the most widely used drug against malaria, except for those cases caused by chloroquine resistant Plasmodium falciparum. Although the mechanism of action is not fully understood, chloroquine is shown to inhibit the parasitic enzyme heme polymerase that converts the toxic heme into non-toxic hemazoin, thereby resulting in the accumulation of toxic heme within the parasite. Chloroquine may also interfere with the biosynthesis of nucleic acids." @default.
- NCIT_C65318 NCIT_A6 NCIT_C61671 @default.
- NCIT_C65318 NCIT_NHC0 "C65318" @default.
- NCIT_C65318 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C65318 NCIT_P108 "Chloroquine Hydrochloride" @default.
- NCIT_C65318 NCIT_P207 "C1383389" @default.
- NCIT_C65318 NCIT_P210 "3545-67-3" @default.
- NCIT_C65318 NCIT_P319 "NT0J0815S5" @default.
- NCIT_C65318 NCIT_P322 "FDA" @default.
- NCIT_C65318 NCIT_P350 "C18H26ClN3.2HCl" @default.
- NCIT_C65318 NCIT_P366 "Chloroquine_Hydrochloride" @default.
- NCIT_C65318 normalizedInformationContent "100" @default.
- NCIT_C65318 referenceCount "1" @default.
- NCIT_C65318 hasExactSynonym "CHLOROQUINE HYDROCHLORIDE" @default.
- NCIT_C65318 hasExactSynonym "Chloroquine Hydrochloride" @default.
- NCIT_C65318 inSubset NCIT_C63923 @default.
- NCIT_C65318 type Class @default.
- NCIT_C65318 isDefinedBy ncit.owl @default.
- NCIT_C65318 label "Chloroquine Hydrochloride" @default.
- NCIT_C65318 subClassOf NCIT_C1908 @default.
- NCIT_C65318 subClassOf NCIT_C1909 @default.
- NCIT_C65318 subClassOf NCIT_C254 @default.
- NCIT_C65318 subClassOf NCIT_C271 @default.
- NCIT_C65318 subClassOf NCIT_C276 @default.
- NCIT_C65318 subClassOf NCIT_C277 @default.
- NCIT_C65318 subClassOf NCIT_C65318 @default.