Matches in Ubergraph for { <http://purl.obolibrary.org/obo/NCIT_C65538> ?p ?o ?g. }
Showing items 1 to 29 of
29
with 100 items per page.
- NCIT_C65538 IAO_0000115 "The S-isomer of omeprazole, with gastric proton pump inhibitor activity. In the acidic compartment of parietal cells, esomeprazole is protonated and converted into the active achiral sulfenamide; the active sulfenamide forms one or more covalent disulfide bonds with the proton pump hydrogen-potassium adenosine triphosphatase (H+/K+ ATPase), thereby inhibiting its activity and the parietal cell secretion of H+ ions into the gastric lumen, the final step in gastric acid production. H+/K+ ATPase is an integral membrane protein of the gastric parietal cell." @default.
- NCIT_C65538 NCIT_A5 NCIT_C29032 @default.
- NCIT_C65538 NCIT_A5 NCIT_C65539 @default.
- NCIT_C65538 NCIT_NHC0 "C65538" @default.
- NCIT_C65538 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C65538 NCIT_P108 "Esomeprazole" @default.
- NCIT_C65538 NCIT_P207 "C0937846" @default.
- NCIT_C65538 NCIT_P210 "119141-88-7" @default.
- NCIT_C65538 NCIT_P319 "N3PA6559FT" @default.
- NCIT_C65538 NCIT_P322 "FDA" @default.
- NCIT_C65538 NCIT_P325 "A drug that blocks acid from being made in the stomach. It is used to treat acid reflux disease and to prevent certain types of gastrointestinal ulcers. Esomeprazole is being studied in the prevention of esophageal cancer and in the treatment of other conditions, including side effects of chemotherapy. It is a type of anti-ulcer agent." @default.
- NCIT_C65538 NCIT_P350 "C17H19N3O3S" @default.
- NCIT_C65538 NCIT_P366 "Esomeprazole" @default.
- NCIT_C65538 NCIT_P368 "CHEBI:50275" @default.
- NCIT_C65538 normalizedInformationContent "100" @default.
- NCIT_C65538 referenceCount "1" @default.
- NCIT_C65538 hasExactSynonym "ESOMEPRAZOLE" @default.
- NCIT_C65538 hasExactSynonym "Esomeprazole" @default.
- NCIT_C65538 hasExactSynonym "esomeprazole" @default.
- NCIT_C65538 inSubset NCIT_C63923 @default.
- NCIT_C65538 type Class @default.
- NCIT_C65538 isDefinedBy ncit.owl @default.
- NCIT_C65538 label "Esomeprazole" @default.
- NCIT_C65538 subClassOf NCIT_C1908 @default.
- NCIT_C65538 subClassOf NCIT_C1909 @default.
- NCIT_C65538 subClassOf NCIT_C29701 @default.
- NCIT_C65538 subClassOf NCIT_C29723 @default.
- NCIT_C65538 subClassOf NCIT_C65538 @default.
- NCIT_C65538 subClassOf NCIT_C78276 @default.