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- NCIT_C657 IAO_0000115 "A nitroimidazole with radiosensitizing and antineoplastic properties. Exhibiting high electron affinity, misonidazole induces the formation of free radicals and depletes radioprotective thiols, thereby sensitizing hypoxic cells to the cytotoxic effects of ionizing radiation. This single-strand breaks in DNA induced by this agent result in the inhibition of DNA synthesis. (NCI04)" @default.
- NCIT_C657 NCIT_A32 NCIT_C1909 @default.
- NCIT_C657 NCIT_NHC0 "C657" @default.
- NCIT_C657 NCIT_P106 "Organic Chemical" @default.
- NCIT_C657 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C657 NCIT_P108 "Misonidazole" @default.
- NCIT_C657 NCIT_P175 "261037" @default.
- NCIT_C657 NCIT_P207 "C0026218" @default.
- NCIT_C657 NCIT_P210 "13551-87-6" @default.
- NCIT_C657 NCIT_P319 "8FE7LTN8XE" @default.
- NCIT_C657 NCIT_P322 "FDA" @default.
- NCIT_C657 NCIT_P322 "GDC" @default.
- NCIT_C657 NCIT_P329 "39504" @default.
- NCIT_C657 NCIT_P330 "39504" @default.
- NCIT_C657 NCIT_P350 "C7H11N3O4" @default.
- NCIT_C657 NCIT_P366 "Misonidazole" @default.
- NCIT_C657 NCIT_P375 "Misonidazole" @default.
- NCIT_C657 NCIT_P399 "39504" @default.
- NCIT_C657 normalizedInformationContent "89.350088392419622" @default.
- NCIT_C657 referenceCount "5" @default.
- NCIT_C657 hasExactSynonym "1-(alpha-methoxymethyl ethanol)-2-Nitroimidazole" @default.
- NCIT_C657 hasExactSynonym "MISONIDAZOLE" @default.
- NCIT_C657 hasExactSynonym "Misonidazole" @default.
- NCIT_C657 hasExactSynonym "RO 7-0582" @default.
- NCIT_C657 hasExactSynonym "Ro-07-0582" @default.
- NCIT_C657 hasExactSynonym "Ro-7-0582" @default.
- NCIT_C657 inSubset NCIT_C128784 @default.
- NCIT_C657 inSubset NCIT_C157711 @default.
- NCIT_C657 inSubset NCIT_C157712 @default.
- NCIT_C657 inSubset NCIT_C176424 @default.
- NCIT_C657 inSubset NCIT_C177537 @default.
- NCIT_C657 inSubset NCIT_C63923 @default.
- NCIT_C657 type Class @default.
- NCIT_C657 isDefinedBy ncit.owl @default.
- NCIT_C657 label "Misonidazole" @default.
- NCIT_C657 subClassOf NCIT_C1908 @default.
- NCIT_C657 subClassOf NCIT_C1909 @default.
- NCIT_C657 subClassOf NCIT_C274 @default.
- NCIT_C657 subClassOf NCIT_C657 @default.
- NCIT_C657 subClassOf NCIT_C798 @default.