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- NCIT_C65974 IAO_0000115 "A beta-adrenergic receptor agonist with bronchodilator activity. Isoetharine selectively binds to beta-2 adrenergic receptors in bronchial smooth muscle, thereby activating intracellular adenyl cyclase, an enzyme that catalyzes the conversion of adenosine triphosphate (ATP) to cyclic-3',5'-adenosine monophosphate (cAMP). Increased cAMP levels cause relaxation of bronchial smooth muscle, relieve bronchospasms, improve mucociliary clearance and reduce mediator substance release from inflammatory cells, especially from mast cells." @default.
- NCIT_C65974 NCIT_A5 NCIT_C65975 @default.
- NCIT_C65974 NCIT_A5 NCIT_C65976 @default.
- NCIT_C65974 NCIT_NHC0 "C65974" @default.
- NCIT_C65974 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C65974 NCIT_P108 "Isoetharine" @default.
- NCIT_C65974 NCIT_P207 "C0022176" @default.
- NCIT_C65974 NCIT_P210 "530-08-5" @default.
- NCIT_C65974 NCIT_P319 "YV0SN3276Q" @default.
- NCIT_C65974 NCIT_P322 "FDA" @default.
- NCIT_C65974 NCIT_P350 "C13H21NO3" @default.
- NCIT_C65974 NCIT_P366 "Isoetharine" @default.
- NCIT_C65974 normalizedInformationContent "100" @default.
- NCIT_C65974 referenceCount "1" @default.
- NCIT_C65974 hasExactSynonym "ISOETHARINE" @default.
- NCIT_C65974 hasExactSynonym "Isoetharine" @default.
- NCIT_C65974 inSubset NCIT_C63923 @default.
- NCIT_C65974 type Class @default.
- NCIT_C65974 isDefinedBy ncit.owl @default.
- NCIT_C65974 label "Isoetharine" @default.
- NCIT_C65974 subClassOf NCIT_C1908 @default.
- NCIT_C65974 subClassOf NCIT_C1909 @default.
- NCIT_C65974 subClassOf NCIT_C29712 @default.
- NCIT_C65974 subClassOf NCIT_C29747 @default.
- NCIT_C65974 subClassOf NCIT_C319 @default.
- NCIT_C65974 subClassOf NCIT_C48149 @default.
- NCIT_C65974 subClassOf NCIT_C65974 @default.
- NCIT_C65974 subClassOf NCIT_C78272 @default.
- NCIT_C65974 subClassOf NCIT_C78273 @default.
- NCIT_C65974 subClassOf NCIT_C87053 @default.