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- NCIT_C66008 IAO_0000115 "A third generation, non-sedating, selective histamine H1 receptor antagonist, with antihistamine, anti-inflammatory and potential anti-angiogenic activities. Levocetirizine competes with endogenous histamine for binding at peripheral H1-receptor sites on the effector cell surface. This prevents the negative symptoms associated with histamine release and an allergic reaction. In addition, as histamine plays an important role in angiogenesis during an allergic inflammatory reaction, blocking the action of histamine may modulate the expression of proangiogenic factors and thus may prevent angiogenesis. As a third-generation histamine H1 receptor antagonist, levocetirizine has fewer side effects than most second-generation antihistamines." @default.
- NCIT_C66008 NCIT_A5 NCIT_C72814 @default.
- NCIT_C66008 NCIT_NHC0 "C66008" @default.
- NCIT_C66008 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C66008 NCIT_P108 "Levocetirizine" @default.
- NCIT_C66008 NCIT_P207 "C1174893" @default.
- NCIT_C66008 NCIT_P210 "130018-77-8" @default.
- NCIT_C66008 NCIT_P319 "6U5EA9RT2O" @default.
- NCIT_C66008 NCIT_P322 "FDA" @default.
- NCIT_C66008 NCIT_P329 "742652" @default.
- NCIT_C66008 NCIT_P330 "742652" @default.
- NCIT_C66008 NCIT_P350 "C21H25ClN2O3" @default.
- NCIT_C66008 NCIT_P366 "Levocetirizine" @default.
- NCIT_C66008 NCIT_P399 "742652" @default.
- NCIT_C66008 normalizedInformationContent "100" @default.
- NCIT_C66008 referenceCount "1" @default.
- NCIT_C66008 hasExactSynonym "LEVOCETIRIZINE" @default.
- NCIT_C66008 hasExactSynonym "Levocetirizine" @default.
- NCIT_C66008 inSubset NCIT_C176424 @default.
- NCIT_C66008 inSubset NCIT_C63923 @default.
- NCIT_C66008 type Class @default.
- NCIT_C66008 isDefinedBy ncit.owl @default.
- NCIT_C66008 label "Levocetirizine" @default.
- NCIT_C66008 subClassOf NCIT_C1908 @default.
- NCIT_C66008 subClassOf NCIT_C1909 @default.
- NCIT_C66008 subClassOf NCIT_C29578 @default.
- NCIT_C66008 subClassOf NCIT_C308 @default.
- NCIT_C66008 subClassOf NCIT_C66008 @default.