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- NCIT_C66117 IAO_0000115 "The sodium salt of methohexital, a rapid, short-acting barbituric acid derivative, with anesthetic activity. Methohexital binds to the chloride ionophore site of the gamma-aminobutyric acid (GABA)-A/chloride ionophore receptor complex, thereby enhancing the inhibitory actions of GABA-A in the brain. This leads to synaptic inhibition, decreased neuronal excitability and induction of anesthesia. In addition, this agent decreases glutamate (Glu) responses." @default.
- NCIT_C66117 NCIT_NHC0 "C66117" @default.
- NCIT_C66117 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C66117 NCIT_P108 "Methohexital Sodium" @default.
- NCIT_C66117 NCIT_P207 "C0304448" @default.
- NCIT_C66117 NCIT_P210 "309-36-4" @default.
- NCIT_C66117 NCIT_P319 "60200PNZ7Q" @default.
- NCIT_C66117 NCIT_P322 "CPTAC" @default.
- NCIT_C66117 NCIT_P322 "FDA" @default.
- NCIT_C66117 NCIT_P350 "C14H17N2O3.Na" @default.
- NCIT_C66117 NCIT_P366 "Methohexital_Sodium" @default.
- NCIT_C66117 NCIT_P368 "CHEBI:6834" @default.
- NCIT_C66117 normalizedInformationContent "100" @default.
- NCIT_C66117 referenceCount "1" @default.
- NCIT_C66117 hasExactSynonym "Brevital" @default.
- NCIT_C66117 hasExactSynonym "METHOHEXITAL SODIUM" @default.
- NCIT_C66117 hasExactSynonym "Methohexital Sodium" @default.
- NCIT_C66117 inSubset NCIT_C156952 @default.
- NCIT_C66117 inSubset NCIT_C156953 @default.
- NCIT_C66117 inSubset NCIT_C159412 @default.
- NCIT_C66117 inSubset NCIT_C63923 @default.
- NCIT_C66117 type Class @default.
- NCIT_C66117 isDefinedBy ncit.owl @default.
- NCIT_C66117 label "Methohexital Sodium" @default.
- NCIT_C66117 subClassOf NCIT_C1908 @default.
- NCIT_C66117 subClassOf NCIT_C1909 @default.
- NCIT_C66117 subClassOf NCIT_C29756 @default.
- NCIT_C66117 subClassOf NCIT_C66117 @default.
- NCIT_C66117 subClassOf NCIT_C67084 @default.
- NCIT_C66117 subClassOf NCIT_C78272 @default.